Article

X-ray crystal structure of the B component of Hemolysin BL fromBacillus cereus

Biology Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
Proteins Structure Function and Bioinformatics (Impact Factor: 2.92). 05/2008; 71(2):534-40. DOI: 10.1002/prot.21888
Source: PubMed

ABSTRACT Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.

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