STIR MRI to direct muscle biopsy in suspected idiopathic inflammatory myopathy.
ABSTRACT Successful management of the idiopathic inflammatory myopathies requires an early and accurate diagnosis. The muscle biopsy remains the definitive test. However, false-negative biopsy results are common, as the disease is typically patchy in distribution. The advent of short tau inversion recovery sequences now allows rapid magnetic resonance imaging of the whole body to be performed, enabling identification of the muscles most suitable for biopsy. It also provides further diagnostic information through the form and anatomic distribution of the pathology. We report 2 cases illustrating the advantages of whole-body short tau inversion recovery magnetic resonance imaging before muscle biopsy. We encourage clinicians to use the technique in this context.
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ABSTRACT: Background: Inflammatory myopathies represent a special group of pathology. Establishing the correct diagnosis in the early phase and a better follow-up are the main objective for improving the life quality of these patients. Objective: The aim of this research was to assess the usefulness of sonoelastography in diagnosis of inflammatory myopathies. Material and Method: A prospective longitudinal study with a control group was carried out in the Radio-Imaging Department, Cluj-Napoca District University Hospital, Romania, from May 2007 to July 2010. Measurements: Image Processing 2.8 software was used to analyze the elastographic images in correlation with clinical and biochemical data was used. Results: Analysis of Receiver Operating Characteristic curves statistics for elastography parameters showed significant values for the following parameters: average green color, average blue color, average intensity of color, dispersion of red, dispersion of green, and dispersion of hue. Conclusions: Our study highlighted the utility of some elastography parameters in the diagnosis of inflammatory myopathies; the parameter proved to be statistically different in case group compared to control. Anyway, standardization of sonoelastography and larger studies are required to ensure accurate diagnosis, reproductibility and reliability.Applied Medical Informatics; Vol 27, No 4 (2010); 81-89.