Article

STIR MRI to direct muscle biopsy in suspected idiopathic inflammatory myopathy.

Department of Medicine, University of Otago School of Medicine, Dunedin Public Hospital, Dunedin, New Zealand.
JCR Journal of Clinical Rheumatology (impact factor: 1.36). 01/2008; 13(6):341-5. DOI:10.1097/RHU.0b013e31815dca0a pp.341-5
Source: PubMed

ABSTRACT Successful management of the idiopathic inflammatory myopathies requires an early and accurate diagnosis. The muscle biopsy remains the definitive test. However, false-negative biopsy results are common, as the disease is typically patchy in distribution. The advent of short tau inversion recovery sequences now allows rapid magnetic resonance imaging of the whole body to be performed, enabling identification of the muscles most suitable for biopsy. It also provides further diagnostic information through the form and anatomic distribution of the pathology. We report 2 cases illustrating the advantages of whole-body short tau inversion recovery magnetic resonance imaging before muscle biopsy. We encourage clinicians to use the technique in this context.

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    Article: Assessment of Sonoelastography as Diagnosis Tool of Inflammatory Myopathies
    Carolina Botar-Jid, Sorana D. BOLBOACĂ, Laura DAMIAN, Sorin M Dudea, Cosmin PANTILIE PANTILIE, Sergiu NEDEVSCHI, Radu Badea
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    ABSTRACT: Background: Inflammatory myopathies represent a special group of pathology. Establishing the correct diagnosis in the early phase and a better follow-up are the main objective for improving the life quality of these patients. Objective: The aim of this research was to assess the usefulness of sonoelastography in diagnosis of inflammatory myopathies. Material and Method: A prospective longitudinal study with a control group was carried out in the Radio-Imaging Department, Cluj-Napoca District University Hospital, Romania, from May 2007 to July 2010. Measurements: Image Processing 2.8 software was used to analyze the elastographic images in correlation with clinical and biochemical data was used. Results: Analysis of Receiver Operating Characteristic curves statistics for elastography parameters showed significant values for the following parameters: average green color, average blue color, average intensity of color, dispersion of red, dispersion of green, and dispersion of hue. Conclusions: Our study highlighted the utility of some elastography parameters in the diagnosis of inflammatory myopathies; the parameter proved to be statistically different in case group compared to control. Anyway, standardization of sonoelastography and larger studies are required to ensure accurate diagnosis, reproductibility and reliability.
    Applied Medical Informatics; Vol 27, No 4 (2010); 81-89.
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Keywords

advantages
 
anatomic distribution
 
biopsy
 
definitive test
 
diagnostic information
 
false-negative biopsy results
 
idiopathic inflammatory myopathies
 
muscle biopsy
 
muscles
 
rapid magnetic resonance imaging
 
short tau inversion recovery sequences
 
whole body
 
whole-body short tau inversion recovery magnetic resonance imaging