The Relationship Between Alcohol Consumption and Glycemic Control Among Patients with Diabetes: The Kaiser Permanente Northern California Diabetes Registry

Kaiser Permanente Division of Research, Oakland, CA 94612, USA.
Journal of General Internal Medicine (Impact Factor: 3.42). 03/2008; 23(3):275-82. DOI: 10.1007/s11606-007-0502-z
Source: PubMed

ABSTRACT Alcohol consumption is a common behavior. Little is known about the relationship between alcohol consumption and glycemic control among people with diabetes.
To evaluate the association between alcohol consumption and glycemic control.
Survey follow-up study, 1994-1997, among Kaiser Permanente Northern California members.
38,564 adult diabetes patients.
Self-reported alcohol consumption, and hemoglobin A1C (A1C), assessed within 1 year of survey date. Linear regression of A1C by alcohol consumption was performed, adjusted for sociodemographic variables, clinical variables, and diabetes disease severity. Least squares means estimates were derived.
In multivariate-adjusted models, A1C values were 8.88 (lifetime abstainers), 8.79 (former drinkers), 8.90 (<0.1 drink/day), 8.71 (0.1-0.9 drink/day), 8.51 (1-1.9 drinks/day), 8.39 (2-2.9 drinks/day), and 8.47 (>/=3 drinks/day). Alcohol consumption was linearly (p < 0.001) and inversely (p = 0.001) associated with A1C among diabetes patients.
Alcohol consumption is inversely associated with glycemic control among diabetes patients. This supports current clinical guidelines for moderate levels of alcohol consumption among diabetes patients. As glycemic control affects incidence of complications of diabetes, the lower A1C levels associated with moderate alcohol consumption may translate into lower risk for complications.

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Available from: Margaret Warton, May 22, 2015
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    • "Studies among both diabetics and nondiabetics demonstrate a J-or U-shaped curve between alcohol consumption and insulin sensitivity (Bell et al. 2000; Davies et al. 2002; Greenfield et al. 2003; Kroenke et al. 2003). Likewise, two large epidemiologic studies among diabetic subjects show that moderate alcohol consumption is associated with better glycemic control (Ahmed et al. 2008; Mackenzie et al. 2006). An important limitation of these studies, however, is that few included ethnic minority groups or failed to emphasize possible differences in relation to ethnicity in their analyses. "
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