Article

Second-harmonic tomography of tissues

Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Optics Letters (Impact Factor: 3.18). 10/1997; 22(17):1323-5. DOI: 10.1364/OL.22.001323
Source: PubMed

ABSTRACT A novel noninvasive second-harmonic-generation tomographic method of mapping the structure of animal tissues by use of 100-fs laser pulses at 625nm is described. Subsurface structures were measured with this approach, which is potentially a symmetry-sensitive tool for optical histological reconstruction.

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