Electronic nose: current status and future trends.

Institute of Physical and Theoretical Chemistry, University of Tübingen, Auf der Morgenstelle 15, Tübingen, Germany.
Chemical Reviews (Impact Factor: 45.66). 03/2008; 108(2):705-25. DOI: 10.1021/cr068121q
Source: PubMed
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    ABSTRACT: Bacterial interactions with neighboring microorganisms via production of small metabolites enable bacteria to respond and adapt to environmental changes. The study of intercellular interactions primarily focused on soluble metabolites, but bacteria also produce and release into their headspace a wide variety of volatile secondary metabolites, the ecological roles of which have generally been overlooked. However, bacterial volatile compounds are known to contribute to interkingdom interactions (plant, fungi and nematodes), and recent studies also identified their at-a-distance influence on bacterial behavior. The present review describes the biological roles of bacterial volatile compounds in inter- and intraspecies bacterial interactions, a new and yet unexplored research area, with potential clinical and industrial applications. © FEMS 2015. All rights reserved. For Permissions, please e-mail:
    FEMS microbiology reviews 03/2015; 39(2). DOI:10.1093/femsre/fuu013 · 13.81 Impact Factor
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    ABSTRACT: There has been an ever-increasing demand for the development of high-performance sensing devices for detection and discrimination of volatile organic compounds (VOCs) present in different environments. Among a number of sensing devices currently available, sorption-based sensors are particularly attractive because they are simple and inexpensive, require low power, and are appropriate for fabrication of multisensor arrays. A sorption-based sensor is comprised of a chemically active coating immobilized on the surface of a physical transducer. The chemically active film interacts with analytes, and the transducer converts the binding event into an electrical signal. This dissertation is focused on a sorption-based sensor prepared by using ionic liquids (ILs) and a group of uniform materials based on organic salts (GUMBOS) as the sensing materials and the quartz crystal microbalance (QCM) as the transducer. ILs are defined as organic salts which melt below 100 °C, and similar organic salts with melting point between 25 and 250 °C are defined as GUMBOS. In this research, a series of films comprising binary blends of an IL (or GUMBOS) and polymer are deposited onto the QCM surface in order to evaluate their vapor-sensing characteristics. The QCM sensors on exposure to organic vapors displayed a change in frequency and motional resistance, and both of these parameters were simultaneously measured. Examination of the data revealed an interesting relationship between the QCM parameters and the molecular weight of the absorbed vapors. The initial findings are reported in Chapter 2 of this dissertation. Additional studies were conducted in an effort to fully understand the interesting behavior of this type of material. More elaborate studies along with the theoretical rationale for the relationship between the QCM parameters and the molecular weight of vapors are presented in Chapter 3. Another important aspect of this dissertation is the design of highly sensitive materials for vapor-sensing applications. Toward this end, two representative GUMBOS were synthesized using porphyrin and phthalocyanine derivatives. The QCM device coated with these GUMBOS exhibited a rapid response and high sensitivity toward different organic vapors. Altogether, these studies demonstrate the true potential of this type of materials for vapor-sensing applications
    08/2014, Degree: PhD, Supervisor: Professor Isiah M. Warner
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    ABSTRACT: Lung cancer (LC) is known as the most common cancers and becoming the leading cause of cancer related death in human. The high mortality in lung cancer patient occurs because of lack of efficient methods to diagnose the disease at an early stage. In this review, we highlighted the studies conducted on compounds in exhaled air breath and metabolic pathway alteration in lung cancer patient, which may influence the alterations of volatile organic compounds (VOCs) in exhaled air breath. This review has shown that VOCs from exhaled air breath of lung cancer patient has potential to be used as lung cancer biomarker to diagnose lung cancer at primary stage by developing advanced technology of electronic nose system. Index Terms— lung cancer, exhaled air breath, metabolic alteration, volatile organic compounds (VOCs), electronic nose system.
    2014 IEEE 5th Control and System Graduate Research Colloquium, UiTM, Shah Alam, Malaysia; 08/2014

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