Dermoscopy of dermatofibromas: a prospective morphological study of 412 cases.
ABSTRACT To describe the dermoscopic features, including vascular structures and patterns associated with dermatofibromas in a large series of cases.
Digital dermoscopic images of the prospectively collected dermatofibromas were evaluated for the presence of multiple structures and patterns.
Dermatofibromas were collected in the Departments of Dermatology of the Hospital de Sant Pau i Santa Tecla, Tarragona, Spain, and Hospital de Sant Llatzer, Palma de Mallorca, Spain.
A total of 412 dermatofibromas (from 292 patients) with complete documentation were collected.
Frequency and intraobserver and interobserver agreement of the dermoscopic structures and patterns in dermatofibromas.
A total of 19 morphological dermoscopic structures were evaluated. Pigment network was observed in 71.8% (3% atypical pigment network), white scarlike patch in 57.0%, and a white network in 17.7%. Different vascular structures were observed in 49.5% (dotted vessels in 30.6%). Ten dermoscopic patterns were observed. The most common pattern seen in our series (34.7% of cases) was central white patch and peripheral pigment network, but in 65.3% of the cases, dermatofibromas presented different patterns including simulators of melanoma.
The most common pattern associated with dermatofibroma is the classic dermoscopic pattern (pigment network and central white patch), but this tumor has a wide range of presentations.
- SourceAvailable from: Vartolomei Mihai Dorin[Show abstract] [Hide abstract]
ABSTRACT: Aneurysmal dermatofibroma (AD) or aneurysmal fibrous histiocytoma (AFH) is a relatively rare form of histiocytoma representing less than 2% of total cases. It shares many clinical and dermoscopic similarities with skin tumors, especially malignant melanoma and Kaposi's sarcoma, which can make differentiation problematic. We report the case of a 53-year-old man, who presents with a black nodular tumor with increased consistency, edges infiltrated from the surface to depth, spontaneous and sensitive to touch that shows rapid growth in the last three months. Dermoscopically, the central region consists of intricate areas colored in red, violet, blue-white and black. On the periphery stand two rings, centrally white and peripherally pigmented, with an abundance of polymorphic capillaries. To clarify the diagnosis, the lesion was widely excised and histopathological examination was performed, which revealed immunophenotypical tumor cells negative for HMB-45 and S100, and numerous CD68 macrophages between tumor cells. This aneurysmal fibrous histiocytoma shows both clinical and dermoscopically discrete differential criteria, which are not specific and that make it difficult to distinguish from malignant melanoma and Kaposi's sarcoma, and required performing histopathology and immunohistochemistry.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 01/2014; 55(Suppl 3):1221-1224. · 0.72 Impact Factor
- Journal of the American Academy of Dermatology 10/2014; 71(4):e123-4. · 5.00 Impact Factor