Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents.

Department of Chemisry IFM and Molecular Imaging Center, University of Torino, Via P. Giuria 7, I-10125, Torino, Italy.
Chemical Communications (Impact Factor: 6.38). 03/2008; DOI: 10.1039/b715383j
Source: PubMed

ABSTRACT Improved LIPOCEST MRI contrast agents with highly shifted intraliposomal water protons were prepared by entrapping neutral polynuclear Tm(III)-based paramagnetic shift reagents in phospholipidic vesicles.

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