Separation of diastereomeric anthrone-C-glucosyls of aloes by micellar electrokinetic capillary chromatography.

Lehrstuhl Pharmazeutische Biologie, Fakultät für Biowissenschaften, Pharmazie und Psychologie, Universität Leipzig, Leipzig, Germany.
Pharmazie (Impact Factor: 0.96). 01/2008; 62(12):955-7. DOI: 10.1691/ph.2007.12.7677
Source: PubMed

ABSTRACT The anthrone-C-glucosyls aloin A and B, 5-hydroxyaloin A, 10-hydroxyaloin A and B were separated by micellar electrokinetic capillary chromatography (MECC) with sodium dodecyl sulfate in borate buffer pH 9 within less than 7 min. The method has been successfully transferred to the analysis of the two European Pharmacopoeia drugs Cape aloes and Curaçao aloes. A comparison of the peak areas received by HPLC and MECC indicated the transferability of the measured contents.