Article

Antibacterial and antifungal activities of Tribulus Terrestris L. growing in Iraq

Department of Biology, College of Education, University of Mosul, Mosul-00964, Iraq.
Journal of Zhejiang University SCIENCE B (Impact Factor: 1.29). 03/2008; 9(2):154-9. DOI: 10.1631/jzus.B0720251
Source: PubMed

ABSTRACT Antimicrobial activity of organic and aqueous extracts from fruits, leaves and roots of Tribulus terrestris L., an Iraqi medicinal plant used as urinary anti-infective in folk medicine, was examined against 11 species of pathogenic and non-pathogenic microorganisms: Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Corynebacterium diphtheriae, Escherichia coli, Proteus vulgaris, Serratia marcescens, Salmonella typhimurium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans using microdilution method in 96 multiwell microtiter plates. All the extracts from the different parts of the plant showed antimicrobial activity against most tested microorganisms. The most active extract against both Gram-negative and Gram-positive bacteria was ethanol extract from the fruits with a minimal inhibitory concentration (MIC) value of 0.15 mg/ml against B. subtilis, B. cereus, P. vulgaris and C. diphtheriae. In addition, the same extract from the same plant part demonstrated the strongest antifungal activity against C. albicans with an MIC value of 0.15 mg/ml.

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    • "There is a need to search for new infection-fighting strategies to control microbial infections. Several studies have been carried out on various medicinal plants screening for their antimicrobial activity (Firas et al., 2008; Yoshikawa et al., 2008; Morales et al., 2008; Parekh and Chanda, 2007; Pesewu et al., 2008). Past two decades, antibacterial properties of various plants and plant parts like root, stem, leaves, seeds and flowers have been well documented for some of the medicinal plants (Nandagopal et al., 2007; Parekh and Chanda, 2007; Akinpelum and Onakoya 2006). "
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    • "However, the last few years have seen a major increase in their use especially in the developed world. There is a growing interest in correlating the phytochemical constituents of a medicinal plant with its pharmacological activity (Costa et al., 2008; Al-Bayati and Al-Mola, 2008). Screening active compounds from plants has lead to the discovery of new medicinal drugs which have shown efficient protective power and treatment roles against various chronic diseases (Fabricant and Fansworth, 2001). "
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