Article

Gastrointestinal symptoms and Helicobacter pylori infection in early pregnancy. A seroepidemiologic study.

Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak, Woman Health Education and Research Hospital, Ankara, Turkey.
Gynecologic and Obstetric Investigation (impact factor: 1.28). 02/2008; 66(1):44-6. DOI:10.1159/000115845 pp.44-6
Source: PubMed

ABSTRACT To investigate the relationship of Helicobacter pylori infection with gastrointestinal symptoms in early pregnancy.
H. pylori seropositivity was determined in 296 pregnant women at 7-12 weeks' gestation by ELISA between January 2004 and April 2007. Sociodemographic characteristics and gastrointestinal symptoms were recorded at this time.
The prevalence of H. pylori infection in our population was 56.8% (168 of 296). 76% of the women with H. pylori and 68% of the women who tested negative for H. pylori infection reported at least one of the evaluated gastrointestinal symptoms. Although morning sickness and morning vomiting were not associated with H. pylori infection, sickness and vomiting during the whole day were more frequently noted with H. pylori infection (OR 2.5, 95% CI 1.2-4.9, p = 0.01).
Of the evaluated gastrointestinal symptoms, H. pylori infection is significantly associated with sickness and vomiting during the whole day.

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Keywords

296 pregnant women
 
7-12 weeks' gestation
 
evaluated gastrointestinal symptoms
 
gastrointestinal symptoms
 
H. pylori
 
H. pylori infection
 
H. pylori seropositivity
 
Helicobacter pylori infection
 
morning vomiting
 
negative
 
prevalence
 
Sociodemographic characteristics
 
vomiting
 
women
 

Abdullah Karaer