Animal trait ontology: The importance and usefulness of a unified trait vocabulary for animal species.

L M Hughes, J. Bao, Z L Hu, V. Honavar, J M Reecy

Department of Animal Science, Center for Integrated Animal Genomics, Iowa State University, 2255 Kildee Hall, Ames 50011, USA.

Journal Article: Journal of Animal Science (impact factor: 2.47). 07/2008; 86(6):1485-91. DOI: 10.2527/jas.2008-0930

Abstract

Ontologies help to identify and formally define the entities and relationships in specific domains of interest. Bio-ontologies, in particular, play a central role in the annotation, integration, analysis, and interpretation of biological data. Missing from the number of bio-ontologies is one that includes phenotypic trait information found in livestock species. As a result, the Animal Trait Ontology (ATO) project being carried out under the auspices of the USDA-National Animal Genome Research Program is aimed at the development of a standardized trait ontology for farm animals and software tools to assist the research community in collaborative creation, editing, maintenance, and use of such an ontology. The ATO is currently inclusive of cattle, pig, and chicken species, and will include other livestock species in the future. The ATO will eventually be linked to other species (e.g., human, rat, mouse) so that comparative analysis can be efficiently performed between species.

Source: PubMed

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Keywords

Animal Trait Ontology
 
annotation
 
ATO
 
auspices
 
bio-ontologies
 
biological data
 
central role
 
collaborative creation
 
comparative analysis
 
farm animals
 
includes phenotypic trait information
 
Ontologies
 
ontology
 
relationships
 
research community
 
software tools
 
standardized trait ontology
 
USDA-National Animal Genome Research Program