Article

Changes in the urinary excretion of beta2-microglobulin (beta 2MG) and N-acetyl-beta-D-glucosaminidase (NAG) during treatment for lupus nephritis.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Internal Medicine (impact factor: 0.94). 02/2008; 47(4):287-90. pp.287-90
Source: PubMed

ABSTRACT Tubulointerstitial involvement in the kidneys is frequently found but it is a less emphasized feature of lupus nephritis (LN). Recent studies have shown increases in the urinary excretion of beta2-microglobulin (beta 2MG) and N-acetyl-beta-D-glucosaminidase (NAG), which are considered to indicate the presence of tubulointerstitial damage, particularly in cases of LN. However, the changes in these urinary parameters during the clinical course of LN have not yet been fully clarified. In this report, we describe the changes in the urinary excretion of beta 2MG and NAG during immunosuppressive treatment combined with double filtration plasmapheresis in a case of LN.

0 0
 · 
0 Bookmarks
 · 
40 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

beta 2MG
 
beta2-microglobulin
 
cases
 
clinical course
 
immunosuppressive treatment
 
lupus nephritis
 
N-acetyl-beta-D-glucosaminidase
 
Recent studies
 
tubulointerstitial damage
 
Tubulointerstitial involvement
 
urinary excretion
 
urinary parameters
 

Takahiro Masuda