Migration of BADGE (bisphenol A diglycidyl-ether) and BFDGE (bisphenol F diglycidyl-ether) in canned seafood

ANFACO-CECOPESCA, Col Univ 16, Vigo, Spain.
Food and Chemical Toxicology (Impact Factor: 2.9). 06/2008; 46(5):1674-80. DOI: 10.1016/j.fct.2008.01.006
Source: PubMed


Migration of potentially toxic materials used for the lining of commercial can goods remains an important issue, especially with respect to certain types of processed foods. Seafood is one type where more information is needed with respect to other ingredients used for adding value to fishery products. Most cans are internally coated with starters of resins such as bisphenol A diglycidyl-ether (BADGE) and bisphenol F diglycidyl-ether (BFDGE), both considered as toxic compounds. Several seafood products, sardines, tuna fish, mackerel, mussels, cod and mackerel eggs, were manufactured in different conditions changing covering sauce, time and temperature of storage and heat-treated for sterilization in cans. Migration kinetics of BADGE and BFDGE from varnish into canned products were evaluated by HPLC in 70 samples after 6, 12 or 18 months of storage. Results showed that there is no migration of BADGE in tuna fish, sardines, mussels or cod. However, migration of BFDGE occurs in all species, in a storage time-dependent way and content of fat, although migration of these compounds is not affected by sterilization conditions. All samples analyzed presented values lower than 9 mg BADGE/kg net product without exceeding European limits. However, concerning BFDGE migration, European legislation does not allow the use and/or the presence of BFDGE. Main migration takes place in mackerel reaching the highest values, 0.74 mg BFDGE/kg and 0.34 mg BADGE/kg net product, in red pepper sauce.

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    • "Nevertheless, there is still controversy over whether low doses of BPA can cause reproductive and developmental effects in humans (Goodman et al. 2006). Significant published data are available on bisphenol A diglycidyl ether (BADGE) or BPA migration from can coatings into foods and food simulants (Biles et al. 1997; Kawamura et al. 1999; Yoshida et al. 2001; Goodson et al. 2002; Kang and Kondo 2003; Cabado et al. 2008), but little is known about how the migration level would be influenced by damage to the can or storage conditions. However, some workers have investigated the effects of the food-processing conditions on the migration of BPA from food or from simulating liquids (Munguıá-Lo´pez and Soto-Valdez 2001; Munguıá-Lo´pez et al. 2005; Sajiki et al. 2005; Poc¸as and Hogg 2007; Le et al. 2008). "
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    • "BPA and BADGE are present in many commonly used products including beverage containers, baby bottles, and dental composites. Both migrate from containers into foods, and are routinely ingested (Cabado et al. 2008; Cao et al. 2009). Studies of BADGE metabolism suggest that it is not a significant source of BPA (Climie et al. 1981) although BPA leaches from some BADGE-containing dental sealants (Joskow et al. 2006; Olea et al. 1996). "
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