To describe the use of botulinum toxin type A (BTX-A) in radiation fibrosis syndrome (RFS).
Retrospective case series.
A large tertiary care cancer center.
Twenty-three consecutive patients treated for sequelae of RFS with BTX-A.
A description of the components of RFS thought to benefit from BTX-A injections and the patient's self-report of benefit from those injections.
The sequelae of RFS for which BTX-A injection was thought to be indicated include radiation-induced cervical dystonia in 18 (78%), trigeminal nerve or cervical plexus neuralgia in 10 (43%), trismus in 7 (30%), migraine in 3 (13%), and thoracic pain in 1 (4%) patient. Most (87%) patients self-reported benefit from the injections.
Initial clinical experience with the use of BTX-A as adjunctive treatment for select neuromuscular and musculoskeletal complications of RFS in a variety of cancer patients has been encouraging. Well-designed prospective studies are needed to clarify the potential beneficial role of BTX-A in specific sequelae of RFS.
"Regardless of the relative commonness of this
condition and its harmful effects on daily functioning and quality of life, there
are only few studies concerning the treatment of limitation of mouth opening and
no standard care exists . Although
physical therapy, hyperbaric oxygen ,
pentoxifylline , botulinum toxin
injection , and surgical coronoidectomy
 have been used for treating the
condition. However, mouth opening appliances provide a conservative approach to
therapy in addition to being easy to use and having better efficacy than physiotherapy
and surgery [14,15]. "
[Show abstract][Hide abstract] ABSTRACT: The principle of leverage to superpose the convex surfaces of two shells was applied to develop a device for treating limitation of mouth opening and called it the "shell-shaped mouth opener" and analyzed pressure on the teeth with the TheraBite(®) appliance and the shell-shaped mouth opening appliance.
To compare the TheraBite(®) appliance and the shell-shaped mouth opening appliance, pressure on the teeth in the dentition model with both devices was analyzed using the Inastomer(®) flexible conductive sensor.
The load was better dispersed to each tooth in the shell-shaped mouth opening appliance in the all quadrants compared to the TheraBite(®) appliance.
The present study revealed that the shell-shaped mouth opening appliance which was originally invented in our lab, dissipated the mechanical load on teeth more evenly than the TheraBite(®) appliance.
[Show abstract][Hide abstract] ABSTRACT: We provide further tests and illustrations of the complete active space based state specific multireference Møller–Plesset perturbation theory (SS-MRMPPT) which opens the way for the treatment of dynamic correlations in situations containing significant static correlations also in an accurate, size- extensive and intruder free manner enjoying at the same time a very favorable computational cost. We have investigated various interesting and computationally challenging systems [H2O, H2O+, BeC, MgC, CO+, Be3, benzene, trimethylenemethane and 1,2,3-tridehydrobenzene] in either their ground, or excited/ionized states. It is found that SS-MRMPPT calculations provide very encouraging results which can be meaningfully compared with other state-of-the-art theoretical estimates. Present results convincingly indicate that the SS-MRMPPT method is not only successful in portraying situations that warrant MR description but also performs acceptably good in cases where a naive single-reference method is enough which reinforces the claim that the SS-MRMPPT is a very useful and flexible ab initio method.
Chemical Physics 06/2012; 401. DOI:10.1016/j.chemphys.2011.04.011 · 1.65 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: The paper investigated the properties of the nonlinear one-dimensional photonic crystals such as reflectivity spectra and field distribution with different value of the nonlinear parameter and a number of nonlinear layers.
Laser and Fiber-Optical Networks Modeling, 2004. Proceedings of LFNM 2004. 6th International Conference on; 10/2004
Jéssica González-Ramos, Elena Sendagorta-Cudós, Guillermo González-López, Ander Mayor-Ibarguren, Rosa Feltes-Ochoa, Pedro Herranz-Pinto
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.