An unusual presentation of atypical fibroxanthoma.
ABSTRACT Atypical fibroxanthoma (AFX) is a rare cutaneous spindle-cell neoplasm. The tumor occurs most commonly in sun-damaged skin of the head and neck in elderly patients. A small subset of patients (approximately one in five cases) is middle-aged and presents with AFX of the trunk or extremities in areas without evidence of actinic damage. We report an unusual case of AFX of the lower leg in an 81-year-old woman with extensive actinic damage.
Article: Nódulo crateriforme en el hélixActas Dermo-Sifiliográficas 10/2011; 102(8):627-628. DOI:10.1016/j.ad.2011.03.008
- Actas Dermo-Sifiliográficas 11/2011; DOI:10.1016/j.adengl.2011.03.009
Article: Case for diagnosis[Show abstract] [Hide abstract]
ABSTRACT: Atypical fibroxanthoma is a rare cutaneous tumor found mainly in elderly people on sun-exposed areas of the body. Histologically, atypical fibroxanthoma is considered a malignant fibrous histiocytoma with bizarre neoplastic cells, marked pleomorphism, hyperchromatic nuclei and abundant mitoses. It must be differentiated from other skin tumors, usually by immunohistochemistry, since its diagnosis is made by exclusion.Anais Brasileiros de Dermatologia 08/2012; 87(4):647-648. DOI:10.1590/S0365-05962012000400026 · 0.87 Impact Factor