A note on twin-singleton differences in asthma.

Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Twin Research and Human Genetics (Impact Factor: 1.92). 05/2008; 11(2):161-4. DOI: 10.1375/twin.11.2.161
Source: PubMed

ABSTRACT Twins constitute a valuable resource for genetic studies of asthma. However, critics argue that twins are 'special' in terms of prenatal environment and upbringing and therefore nonrepresentative. In respect to asthma a small range of studies report differential morbidity in twins compared with singletons. We review some of the possible explanations for these findings and conclude that results from twin studies of asthma can be extrapolated to the general population.

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