Article

Relation of bone mineral density to frequency of coronary heart disease.

Department of Medicine, Cardiology Division, New York Medical College, Valhalla, New York, USA.
The American Journal of Cardiology (impact factor: 3.37). 04/2008; 101(8):1103-4. DOI:10.1016/j.amjcard.2007.12.013 pp.1103-4
Source: PubMed

ABSTRACT Coronary angiography was performed because of chest pain in 198 patients (146 women, 52 men; mean age 66 years) who had dual-energy x-ray absorptiometry scans of the spine and left hip because of suspected osteoporosis or osteopenia. Of the 198 patients, 53 (27%) had osteoporosis, 79 (40%) had osteopenia, and 66 (33%) had normal bone mineral density (BMD). Obstructive coronary artery disease with >50% narrowing of > or =1 major coronary artery was present in 40 of 53 patients (76%) with osteoporosis, in 54 of 79 patients (68%) with osteopenia, and in 31 of 66 patients (47%) with normal BMD (p <0.005 comparing osteoporosis with normal BMD, p <0.01 comparing osteopenia with normal BMD). In conclusion, in patients who undergo coronary angiography because of chest pain, patients with osteoporosis or osteopenia have a higher prevalence of obstructive coronary artery disease than those with normal BMD.

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Keywords

53 patients
 
66 patients
 
79 patients
 
age 66 years
 
BMD
 
chest pain
 
Coronary angiography
 
higher prevalence
 
normal BMD
 
obstructive coronary artery disease
 
osteoporosis
 
patients