Experimental models for research and training in renal transplant

Servicio de Urología, Hospital de Fuenlabrada, Madrid.
Actas urologicas españolas (Impact Factor: 1.02). 02/2008; 32(1):83-90.
Source: PubMed


An update on aspects and use of different experimental models applied in kidney transplant research is presented . This paper includes qualities, as long as similarities between most frequently used animal models and human clinical standards. Contributions of those models based on microsurgical or laparoscopic techniques are revised. The physiological consequences (hemodynamic, immunologic) of surgical technique (laparoscopy), applied in experimental models as long as non-heart beating organ donor models and organ preservation methods are also reviewed. Finally, an update of those models applied in research in prothocols of either immunosupression or xenotransplant is done.

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