Article

Impact of state and trait anxiety on the panic response to CCK-4.

Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany.
Acta Neurovegetativa (impact factor: 2.73). 07/2008; 115(6):917-20. DOI:10.1007/s00702-008-0047-2 pp.917-20
Source: PubMed

ABSTRACT In order to elucidate the impact of psychological factors on panic severity the correlation between baseline anxiety and panic response to cholecystokinin-tetrapeptide (CCK-4), an established model of human anxiety, was investigated in 33 healthy volunteers. Baseline anxiety was assessed with the State-Trait-Anxiety-Inventory (STAI). Trait and state anxiety did not differ between panickers and nonpanickers nor were they correlated with panic severity. In conclusion, psychological factors are not major determinants for the subjective panic response to CCK-4 thus emphasising the importance of neurobiological factors.

0 0
 · 
0 Bookmarks
 · 
37 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

33 healthy volunteers
 
Baseline anxiety
 
elucidate
 
established model
 
human anxiety
 
neurobiological factors
 
nonpanickers
 
panic response
 
panic severity
 
panickers
 
psychological factors
 
STAI
 
state anxiety
 
State-Trait-Anxiety-Inventory
 
subjective panic response