Article

Serum levels of zinc and copper in hydatidiform mole.

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Harran, Sanliurfa, Turkey.
Archives of Gynecology and Obstetrics (impact factor: 1.28). 04/2005; 271(4):304-6. DOI:10.1007/s00404-004-0614-1 pp.304-6
Source: PubMed

ABSTRACT The aim of this study was to identify any association between serum levels of trace elements zinc and copper and development of hydatidiform mole.
Blood samples of 35 patients with complete hydatidiform mole and 34 pregnant women controls were evaluated for serum levels of zinc and copper. Student's t-test was used for comparison of mean values of serum zinc and copper and for demographic variables. p< or =0.05 was considered statistically significant.
Levels of zinc in serum were found to be significantly higher in hydatidiform mole patients than controls (86.3 vs. 68.7 microg/l, p=0.027). Serum copper levels were significantly lower in hydatidiform mole patients than controls (123.8 vs. 147.8 microg/l, p=0.039; Table 2).
This is the first study in the English scientific literature reporting higher serum levels of zinc and lower serum levels of copper associated with complete hydatidiform mole.

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Keywords

34 pregnant women controls
 
Blood samples
 
complete hydatidiform mole
 
demographic variables
 
English scientific literature
 
higher serum levels
 
hydatidiform mole
 
hydatidiform mole patients
 
lower serum levels
 
serum levels
 
serum zinc
 
Student's t-test
 
Table 2
 
trace elements zinc
 
zinc
 

Mehmet Harma