Serum levels of zinc and copper in hydatidiform mole.
ABSTRACT The aim of this study was to identify any association between serum levels of trace elements zinc and copper and development of hydatidiform mole.
Blood samples of 35 patients with complete hydatidiform mole and 34 pregnant women controls were evaluated for serum levels of zinc and copper. Student's t-test was used for comparison of mean values of serum zinc and copper and for demographic variables. p< or =0.05 was considered statistically significant.
Levels of zinc in serum were found to be significantly higher in hydatidiform mole patients than controls (86.3 vs. 68.7 microg/l, p=0.027). Serum copper levels were significantly lower in hydatidiform mole patients than controls (123.8 vs. 147.8 microg/l, p=0.039; Table 2).
This is the first study in the English scientific literature reporting higher serum levels of zinc and lower serum levels of copper associated with complete hydatidiform mole.