Comorbidity of asthma and anxiety and depression in Puerto Rican children

Department of Epidemiology, Columbia University, New York, New York, United States
Psychosomatics (Impact Factor: 1.67). 03/2004; 45(2):93-9. DOI: 10.1176/appi.psy.45.2.93
Source: PubMed

ABSTRACT Studies have reported that childhood asthma is associated with internalizing disorders, but most of these studies have used global measures of depressive and anxiety symptoms. The Diagnostic Interview Schedule for Children was administered to a group of 1891 youth ages 4 to 17 and their caregivers in Puerto Rico to determine DSM-IV symptoms and diagnoses. Asthma diagnosis and having had an asthma attack were assessed by parental report. A diagnosis of asthma was associated with having any depressive disorder and one symptom of separation anxiety. An asthma attack was associated with any depressive disorder and any anxiety disorder and, more specifically, with separation anxiety disorder, major depressive disorder, and symptoms of depression, separation anxiety, and generalized anxiety. Possible explanations for the findings are discussed.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Abstract Objective: To investigate the prevalence of asthma and mental health problems among representative samples of youth in high risk service settings and the community, and to examine the relationship between asthma and mental health in these groups. Methods: Data were drawn from the Alternative Service Use Patterns of Youth with Serious Emotional Disturbance Study (SED) (n=1,181), a combined representative, cross-sectional sample of youth in various clinical settings and the community. Multiple logistic regression analyses were used to examine the association between asthma and mental disorders. Demographic characteristics were investigated as potential confounders. Results: Asthma was common among 15.2% of youth in service settings and 18.8% of youth in the community. The prevalence of mental disorders was extremely high among youth with and without asthma in all service settings, and asthma was associated with increased prevalence of mental disorders among youth in the community, but not among youth in service settings. The relationship between asthma and internalizing disorders among youth in the community does not appear entirely attributable to confounding by demographics. Conclusions: Findings are consistent with and extend previous data by showing that both asthma and mental disorders are disproportionately common among youth in high risk service settings. Almost half of youth with asthma in service settings meet diagnostic criteria for a mental disorder. Clinicians and policy makers who are responsible for the health care of youth in these high risk groups should be aware that asthma is common, and that the prevalence of internalizing disorders are especially common among those with asthma.
    Journal of Asthma 03/2014; DOI:10.3109/02770903.2014.897728 · 1.83 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: World-wide more than one hundred million people suffer from asthma. This population presents a high prevalence of major depressive disorder (MDD) and generalized anxiety disorder (GAD). However, this association has not been investigated IN Colombian asthma outpatients. Objective: To establish whether asthma severity is associated with MDD or GAD in adult asthma outpatients in Bucaramanga, Colombia. Method: A study on cases (44 patients with severe asthma) and controls (88 patients with mild asthma), matched according to age, sex and socioeconomic status, was designed. The current MDD and GAD diagnoses were made using the Structured Clinical Interview for D SM-IV Axis I Disorders-Clinical version (SCID-CV). Results: The current prevalencE of MDD WAS 27.2% and 29.5% in patients with mild asthma and patients with severe asthma, respectively (OR=1.12, 95% CI 0.46- 2.69). The prevalence of GAD was 43.1% and 45.4% in patients with mild asthma and patients with severe asthma, respectively (OR=1.10, 95% CI 0.49-2.44). Conclusion: There is no association between MMD and GAD and the degree of severity in asthma patients in Bucaramanga, Colombia.
    09/2009; 38(3):464-470.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Objective To determine whether maternal mental health mediates the relationship between eczema or asthma symptoms and mental well-being in children. Study design Analysis of 7250 children from the Avon Longitudinal Study of Parents and Children. Child mental well-being at 8 years was measured by the Strengths and Difficulties Questionnaire. Binary outcomes were high ‘internalizing’ (anxious/depressive) and ‘externalizing’ (oppositional/hyperactive) problems (high was >90th percentile). Child rash and wheeze categories were ‘none’; ‘early onset transient’ (infancy/preschool only); ‘persistent’ (infancy/preschool and at school age); and ‘late onset’ (school age only). Maternal anxiety and depression were reported during pregnancy and when child was 8 years old. Results Persistent wheezing symptoms were associated with high externalizing (OR 1.74, 95% CI, 1.41-2.15) and internalizing (1.67, 1.35-2.06) problems compared with never wheeze. Maternal anxiety and depression, and disrupted child sleep, attenuated these associations. Persistent rash (externalizing: 1.74, 1.40-2.15; internalizing: 1.42, 1.16-1.74) and late onset rash (externalizing: 1.62, 1.17-2.25; internalizing: 1.46, 1.07-1.99) symptoms were associated with poorer mental well-being compared with no rash at any age. Maternal anxiety and depression, particularly when child was aged 8 years rather than during pregnancy, accounted for the association with internalizing symptoms and partly for externalizing symptoms. Sleep disruption did not mediate the association. Conclusions Maternal anxiety and depression may mediate the association between child rash and wheeze and child mental well-being.
    Journal of Pediatrics 06/2014; 165(3). DOI:10.1016/j.jpeds.2014.05.023 · 3.74 Impact Factor

Full-text (2 Sources)

Available from
May 19, 2014