Subungual blue nevus with combined phenotypic features
Department of Dermatology, Brown Medical School, Providence, Rhode Island 02903, USA.Journal of the American Academy of Dermatology (Impact Factor: 4.45). 07/2008; 58(6):1021-4. DOI: 10.1016/j.jaad.2008.02.030
Blue nail dyschromia may represent melanocytic, vascular, or other etiologies. A case of a subungual blue nodule is presented, with a pseudo-clubbed nail. On histopathologic examination, there was a combined subungual blue nevus, with features of a common blue nevus and a pigmented epithelioid melanocytoma. This unusual presentation is reviewed, with a discussion of blue nail dyschromia and subungual blue nevi.
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ABSTRACT: Melanonychia is black or brown pigmentation that appears in the fingernails and toenails. The pigment can come from exogenous sources, such as bacteria or fungal infection, tar, or blood. Endogenous causes include aberrant melanin production in the nail bed, resulting in a longitudinal presentation. Melanonychia can indicate the presence of cancerous growths, as well as infection. Diagnostic measures, including dermatoscopy, biopsy, and histopathology, can determine the cause and direct the course of treatment. Malignant lesions should be excised, and underlying infections should be addressed with antibiotics or antifungals. Benign lesions and hyperpigmentation may benefit from a wait-and-see approach.Clinics in dermatology 09/2013; 31(5):594-601. DOI:10.1016/j.clindermatol.2013.06.007 · 2.47 Impact Factor
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ABSTRACT: Subungual pigmented lesions should raise concern about malignant melanoma. Blue naevus of the nail apparatus is a rare entity, with only ten cases described in the literature. We report a 21-year-old Hispanic woman with a slowly enlarging 1.7 x 2.3-cm subungual and periungual pigmented plaque present since birth on her right second toe. Initial biopsy was consistent with a blue naevus of the cellular type and, given the recent clinical change and periungual extension, complete excision was recommended. The entire nail unit was resected down to periosteum with prior avulsion of the nail plate. Reconstruction was performed with a full-thickness skin graft. Follow up at 1 year revealed well-healed graft and donor sites with complete return of function. We present a case of a congenital subungual and periungual blue naevus of the cellular type and review the literature on this rare presentation of a congenital blue naevus.Australasian Journal of Dermatology 06/2009; 50(2):144-7. DOI:10.1111/j.1440-0960.2008.00501.x · 1.11 Impact Factor
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