Preliminary study of the use of drug-eluting stents in atherosclerotic renal artery stenoses 4 mm in diameter or smaller.
ABSTRACT To describe restenosis and clinical outcomes with drug-eluting stents (DESs) and compare them to those of bare metal stents (BMSs) in the treatment of symptomatic atherosclerotic renal artery stenosis (RAS) in the same patients.
A retrospective study was performed of all patients with RAS treated with a DES (Taxus Express 2 or Cypher). DESs were used for RASs with luminal vessel diameters of 4 mm or smaller and BMSs were used for those larger than 4 mm.
Sixteen patients (eight women; mean age, 72 years +/- 8) underwent treatment of 27 RASs for worsening renal function (n = 10) and uncontrolled hypertension (n = 6). Eighteen RASs were treated with 23 DESs (Cypher, n = 12; Taxus, n = 11) and nine were treated with BMSs. The average follow-up was 22 months +/- 10. After the procedure, the mean systolic blood pressure decreased significantly (P < .05), with no change in the mean diastolic pressure, serum creatinine, or number of antihypertensive medications. By Kaplan-Meier estimates, the 1- and 2-year patency rates for DESs were 78% and 68%, respectively; and for BMSs, the respective rates were 58% and 47% (P = NS). The average diameters of RASs were 3.4 mm +/- 0.6 in the DES group and 5.3 mm +/- 0.6 in the BMS group (P < .05). There were two technical failures (7.7%) in the DES group. There was one minor complication and a non-flow-limiting dissection.
DESs were used to treat RASs with good technical results and low restenosis rates compared with BMSs despite the smaller artery diameters in the DES group.
- SourceAvailable from: psych.imng.comAnnales De Chirurgie Vasculaire. 01/2010; 9(1):18-18.
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ABSTRACT: IntroductionWe report a case of combined endovascular and surgical treatment in a patient with Takayasu's arteritis-induced bilateral renal artery occlusion.ReportA 38-year-old women suffering from Takayasu's arteritis-induced renal artery stenosis (TARAS) was referred to our centre. The patient also complained of claudication and of symptoms related to ostial stenosis of superior mesenteric artery. She was treated with a sequence of open and endovascular procedures and is now on a 3-year uneventful follow-up.DiscussionTo our knowledge, this is the first case of combined endovascular and surgical treatment of TARAS performed simultaneously in one operative procedure that has ever been reported in the literature.EJVES Extra 01/2010; 39(2):249-249.
- Gastroenterology 01/2011; 140(5). · 12.82 Impact Factor