Multiple small-bowel intussusceptions caused by metastatic malignant melanoma.
ABSTRACT Intussusceptions of the small bowel, along with multiple intraluminal metastatic tumors, were noted during surgery. A segmental resection of the small bowel was performed, and the histologic diagnosis of metastatic melanoma was made. Long-term survival remains poor; therefore, complete surgical resection of macroscopic tumors remains the best treatment of choice.
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ABSTRACT: To characterize clinical features, surgery, outcome, and survival of malignant melanoma (MM) of the gastrointestinal (GI) tract in a surgical training center in Bangkok, Thailand. A retrospective review was performed for all patients with MM of the GI tract treated at our institution between 1997 and 2007. Fourteen patients had GI involvement either in a metastatic form or as a primary melanoma. Thirteen patients with sufficient data were reviewed. The median age of the patients was 66 years (range: 32-87 years). Ten patients were female and three were male. Seven patients had primary melanomas of the anal canal, stomach and the sigmoid colon (5, 1 and 1 cases, respectively). Seven patients underwent curative resections: three abdominoperineal resections, two wide local excisions, one total gastrectomy and one sigmoidectomy. Six patients had distant metastatic lesions at the time of diagnosis, which made curative resection an inappropriate choice. Patients who underwent curative resection exhibited a longer mean survival time (29.7 mo, range: 10-96 mo) than did patients in the palliative group (4.8 mo, P = 0.0006). GI MM had an unfavorable prognosis, except in patients who underwent curative resection (53.8% of cases), who had a mean survival of 29.7 mo.World Journal of Gastroenterology 02/2010; 16(6):745-8. · 2.55 Impact Factor
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ABSTRACT: Localized malignant pleural mesothelioma (LMPM) is a rare occurrence, and gastrointestinal intra-luminal metastases have not previously been reported. Herein, we report a patient with LMPM who presented with a local recurrence 10 mo after initial en bloc surgical resection. Abdominal computed tomography was performed for intractable, vague abdominal pain with episodic vomiting, which showed a "target sign" over the left lower quadrant. Laparotomy revealed several intra-luminal metastatic tumors in the small intestine and colon and a segmental resection of metastatic lesions was performed. Unfortunately, the patient died of sepsis despite successful surgical intervention. Though local recurrence is more frequent in LMPM, the possibility of distant metastasis should not be ignored in patients with non-specific abdominal pain.World Journal of Gastroenterology 08/2010; 16(31):3984-6. · 2.55 Impact Factor