Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the prevention of relapse and recurrence in major depression.

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.
Journal of Consulting and Clinical Psychology (Impact Factor: 4.85). 07/2008; 76(3):468-77. DOI: 10.1037/0022-006X.76.3.468
Source: PubMed

ABSTRACT This study followed treatment responders from a randomized controlled trial of adults with major depression. Patients treated with medication but withdrawn onto pill-placebo had more relapse through 1 year of follow-up compared to patients who received prior behavioral activation, prior cognitive therapy, or continued medication. Prior psychotherapy was also superior to medication withdrawal in the prevention of recurrence across the 2nd year of follow-up. Specific comparisons indicated that patients previously exposed to cognitive therapy were significantly less likely to relapse following treatment termination than patients withdrawn from medication, and patients previously exposed to behavioral activation did almost as well relative to patients withdrawn from medication, although the difference was not significantly different. Differences between behavioral activation and cognitive therapy were small in magnitude and not significantly different across the full 2-year follow-up, and each therapy was at least as efficacious as the continuation of medication. These findings suggest that behavioral activation may be nearly as enduring as cognitive therapy and that both psychotherapies are less expensive and longer lasting alternatives to medication in the treatment of depression.

  • [Show abstract] [Hide abstract]
    ABSTRACT: In recent decades cognitive-behavioral therapy (CBT) and decision science (DS) have emerged within the field of psychological science. Though these are two vastly different areas of study, they are similar in that they address human information processing, cognition, behavior, and the link between them. In this article, we provide brief summaries of CBT and decision science, discuss their similarities and differences, and discuss how future research can identify ways in which these fields can inform each other. Several CBT techniques that might be of use to the efforts of the decision science field to prevent cognitive biases are suggested. Research that integrates these two fields may lead to the improvement of both.
    New Ideas in Psychology 12/2013; 31(3):173-183. · 0.86 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: By 2020, depression is projected to be among the most important contributors to the global burden of disease. A plethora of data confirms that despite the availability of effective therapies, major depressive disorder continues to exact an enormous toll; this, in part, is due to difficulties reaching complete remission, as well as the specific associated costs of both the disorder's morbidity and mortality. The negative effects of depression include those on patients' occupational functioning, including absenteeism, presenteeism, and reduced opportunities for educational and work success. The use of management algorithms has been shown to improve treatment outcomes in major depressive disorder and may be less costly than "usual care" practices. Nevertheless, many patients with depression remain untreated. As well, even those who are treated often continue to experience suboptimal quality of life. As such, the treatment algorithms in this article may improve outcomes for patients suffering with depression. This paper introduces some of the principal reasons underlying these treatment gaps and examines measures or recommendations that might be changed or strengthened in future practice guidelines to bridge them. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
    Psychiatry Research 12/2014; 220S1:S3-S14. · 2.68 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Cómo Referenciar este artículo/How to reference this article: Basto, I. y Salgado, J. (2014). La investigación sobre el proceso de cambio en psicoterapia y los diferentes enfoques terapéuticos: un análisis de los mecanismos cognitivos y emocionales. Revista de Psicoterapia, 25(99), 31-47. Resumen Actualmente, la investigación sobre la efectividad de los diferentes tipos de psicoterapia demuestra que la psicoterapia funciona para distintos tipos de trastornos. Sin embargo, todavía hay varios problemas que siguen sin resolverse, por ejemplo, los casos que no responden al tratamiento así como casos de deterioro. Con esta finalidad, es necesario complementar la investigación de eficacia con estudios de proceso (investigación de proceso y proceso-resultado). Así este trabajo tiene como objetivos: efectuar una breve síntesis del estado actual de la investigación sobre los mecanismos de cambio (emocio-nales y cognitivos) en la psicoterapia; y w. El análisis de los diferentes estudios parece validar empíricamente el papel mediador de diferentes mecanismos en la promoción del cambio terapéutico. Sin embargo, parece ser más difícil confirmar la especificidad de los mecanismos a las terapias que los suscitan específicamente. Se discutirá las implicaciones de estos resultados para investigaciones futuras sobre el cambio terapéu-tico. Palabras Clave: Psicoterapia; Cambio terapéutico; Investigación Proceso-resul-tado; mecanismos de cambio.
    01/2014; 25(99):31-47.

Full-text (2 Sources)

Available from
May 16, 2014