Malignant Peripheral Nerve Sheath Tumor Arising from an Adrenal Ganglioneuroma in a 6-Year-old Boy

Department of Pathology and Laboratory Medicine, St. Christopher's Hospital for Children, and Drexel University College of Medicine, Philadelphia, PA 19134, USA.
Pediatric and Developmental Pathology (Impact Factor: 0.87). 05/2004; 7(3):277-84. DOI: 10.1007/s10024-004-8084-9
Source: PubMed


This report describes the youngest patient to develop a malignant peripheral nerve sheath tumor arising from a ganglioneuroma (MPNST ex Ganglioneuroma). The patient, a 6-year-old boy, was never irradiated and had no history or stigmata of neurofibromatosis. The report also includes a review of the previously published related cases, and an analysis of the immunohistochemistry and electron microscopy data available to date on the subject.

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