Anatomic Variations of the Sphenoid Sinus and Their Impact on Trans-sphenoid Pituitary Surgery.

Department of Otorhinolaryngology, Ain Shams University, Cairo, Egypt.
Skull Base Surgery (Impact Factor: 0.6). 02/2008; 18(1):9-15. DOI: 10.1055/s-2007-992764
Source: PubMed

ABSTRACT Introduction: The trans-sphenoid access to the pituitary gland is becoming the most common approach for pituitary adenomas. Preoperative evaluation of the anatomy of the sphenoid sinus by computed tomography (CT) scan and magnetic resonance imaging (MRI) is a routine procedure and can direct the surgical decision. Purpose: This work determines the incidence of the different anatomical variations of the sphenoid sinus as detected by MRI and CT scan and their impact on the approach. Methods: The CT scan and MRI of 296 patients operated for pituitary adenomas via a trans-sphenoid approach were retrospectively reviewed regarding the different anatomical variations of the sphenoid sinus: degree of pneumatization, sellar configuration, septation pattern, and the intercarotid distance. Results: There were 6 cases with conchal pneumatization, 62 patients with presellar, 162 patients with sellar, and 66 patients with postsellar pneumatization. There was sellar bulge in 232 patients, whereas this bulge was absent in 64 patients. There was no intersphenoid sinus septum in 32 patients, a single intersphenoid septum in 212 patients, and an accessory septum in 32 patients. Intraoperatively, the sellar bulge was marked in 189 cases and was mild in 43 cases. Discussion: The pattern of pneumatization of the sphenoid sinus significantly affects the safe access to the sella. A highly pneumatized sphenoid sinus may distort the anatomic configuration, so in these cases it is extremely important to be aware of the midline when opening the sella to avoid accidental injury to the carotid and optic nerves. The sellar bulge is considered one of the most important surgical landmarks, facilitating the access to the sella. The surgical position of the patient is also a crucial point to avoid superior or posterior misdirection with resultant complications. It is wise to use extreme caution while removing the terminal septum. Conclusion: Different anatomical configurations of the sphenoid sinus can seriously affect the access to the sella via the nose. The surgeon should be aware of these findings preoperatively to reach the sella safely and effectively.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Sphenoid sinus has got importance due to trans-sphenoid approach to the pituitary gland. This study is an attempt to know the variations in North Karnataka population, through cadaveric dissection and CT scan study. Objective: We want to study variations in sphenoid sinus and its percentage in North Karnataka population. Material and Methods: Endoscopic examination and dissection of sphenoid sinus was carried out in 30 cadavers (three female and 27 male) using 0°, 30°, 70° rigid nasal endoscopes. Sections were then made in the sagittal plane to confirm the anatomical findings and to take the necessary measurements with millimeter strips. Results: In six of cadavers pre-sellar, in four it was sellar and in 20 it was post-sellar while conchal type of sphenoid sinus was absent. The septa terminated on bone covering internal carotid artery (ICA) in seven cadavers while in two cadavers they terminated on the bone covering Optic nerve (ON). Findings of CT scan study were pre-sellar-8, sellar-14 and post-sellar-37 and in case of one subject left side sinus was conchal. Pneumatization of greater wing of sphenoid was observed in two sinuses, of pterygoid process in four sinuses and of anterior clinoid process in two sinuses. We also found onodi cell in one sinus. Conclusion: Sphenoid sinus shows various types of pneumatisation, and this place the sinus in close proximity to important neurovascular structures that are present around the sinus. Newer techniques are used to confirm surgical landmarks making these techniques very safe.
    Journal of clinical and diagnostic research : JCDR. 04/2014; 8(4):AC01-5.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: A conchal non-pneumatized sphenoid sinus was previously considered to be a contraindication to the endoscopic transsphenoidal route to the sella due to its small sellar floor and poor anatomical landmarks, such as the optic nerve canal, opticocarotid recess and internal carotid arteries canal. The present study aimed to investigate the methodology and characteristics of the endoscopic transsphenoidal resection of sellar tumors with a conchal sphenoid sinus. Two patients with sellar tumor patients and non-pneumatized sphenoid sinuses received endoscopic transsphenoidal surgery. The two conchal sphenoid sinuses were accessed safely, total resection was achieved and no serious complications occurred. Therefore, the presence of a conchal non-pneumatized sphenoid is not an absolute contraindication for employing the endoscopic transsphenoidal route in the resection of sellar tumors; a positive outcome may be achieved, in particular when the surgery is performed by an experienced otolaryngologist.
    Oncology letters 02/2015; 9(2):713-716. · 0.99 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Background The rapid evolution of transsphenoidal endoscopic surgical intervention and surgeries of skull base and sellar regions is accompanied by multiple complications. Objective To determine different types of extension of sphenoid sinus pneumatization detected by CT and MRI and their impact upon different approaches and complications of sellar region surgeries. Subjects and methods The pre-operative CT and MRI images of 182 patients with surgical intervention for peri-sellar region pathologies were retrospectively evaluated for patterns of sphenoid pneumatization. Post surgical complications were recorded and analyzed. Results The overall rate of complications was 88 affecting 62 patients (34%), and 120 patients (66%) were free of complications. Different types of pneumatization were detected on CT and MRI images, conchal in 3 cases (1.6%), presellar 23 cases (12.6%) and 156 cases (85.7%) showing sellar pneumatization. Sellar pattern was reclassified into 6 types. Single inter sphenoid septum was seen in 109 patients, accessory septum was found in 13 patients and 10 patients have multiple sphenoid septation. 24 patients (13.2%) show absent septum. Conclusion Pre-intervention assessment of sphenoid sinus pneumatization is mandatory in approaching the sella and skull base structures either via the nose or open skull base surgery to avoid injury of the nearby structures and reduce the possibility of CSF leakage.
    The Egyptian Journal of Radiology and Nuclear Medicine. 09/2014;


Available from
May 22, 2014