Article

Fluorescent silica nanoparticles.

Institute of Analytical Chemsitry, Chemo- and Biosensors, University of Regensburg, D-93040 Regensburg, Germany.
Annals of the New York Academy of Sciences (impact factor: 3.15). 02/2008; 1130:218-23. DOI:10.1196/annals.1430.053 pp.218-23
Source: PubMed

ABSTRACT We report on the preparation of fluorescent silica nanoparticles (NPs). They have been prepared by (a) modification of the NPs by amino groups and subsequent introduction of amino-reactive fluorophores of various color and (b) by modification of the NPs by either azido groups or alkyne groups and subsequent conjugation to fluorophores by so-called click chemistry, which is a novel approach toward modifying silica NPs. The new NPs were characterized in terms of size and spectral properties.

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Keywords

alkyne groups
 
amino groups
 
amino-reactive fluorophores
 
azido groups
 
fluorescent silica nanoparticles
 
fluorophores
 
new NPs
 
so-called click chemistry