Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue

Department of Dermatology, Marmara University School of Medicine, Istanbul, Turkey.
Journal of the American Academy of Dermatology (Impact Factor: 5). 09/2008; 59(2 Suppl 1):S23-4. DOI: 10.1016/j.jaad.2007.09.033
Source: PubMed

ABSTRACT Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue is a benign rare tumor. Thirty cases have been reported so far. It presents as a slowly growing, asymptomatic, submucosal nodule on the anterior dorsum of the tongue. Histopathologically, the tumor is composed of a well-circumscribed, lobular proliferation of fusiform and ovoid cells in a chondromyxoid background. Most consistent immunohistochemical finding is the diffuse and strong immunoreactivity for glial fibrillary acid protein. Histogenetic origin of the tumor is uncertain. We report here a 56-year-old woman with a 0.7-cm tumoral lesion of 5 months' duration on the anterior aspect of her tongue. Total excision was performed and histopathologic findings were consistent with ectomesenchymal chondromyxoid tumor. No recurrence was observed after 2 years of follow-up.

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