Article

[Analysis on human papillomavirus 16 and 18 types infection among 805 patients with common anorectal lesions].

Department of Pathology, The Third Affiliated Hospital, Nanjing Traditional Chinese Medical University, Nanjing 210001, China.
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 12/2011; 14(12):958-60. pp.958-60
Source: PubMed

ABSTRACT To analyze the infection condition of human papillomavirus (HPV) type 16 and 18 in the squamous cells and columnar cells of patients with common anorecatal lesions.
Infections of HPV type 16 and 18 were determined with real-time fluorescent quantitative PCR in the wax-embedded surgical specimen of 805 patients with common anorectal diseases.
The overall infection rate among 805 patients with anorecatal lesions was 66.1% (532/805). The infection rate was 82.6% (95/115) in patients with mixed hemorrhoids, 76.5% (88/115) in anal papillary fibromas, 74.8% (86/115) in internal hemorrhoids, 72.2% (83/115) in fistulas, 69.6% (80/115) in external hemorrhoids, 47.8% (55/115) in anal perianal abscesses, and 39.1% (45/115) in anal fissures.
Infection rate of HPV type 16, 18 in common anorectal lesions is high.

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Keywords

anal papillary fibromas
 
columnar cells
 
common anorecatal lesions
 
common anorectal diseases
 
common anorectal lesions
 
external hemorrhoids
 
fistulas
 
infection condition
 
infection rate
 
Infections
 
internal hemorrhoids
 
mixed hemorrhoids
 
real-time fluorescent quantitative PCR
 
wax-embedded surgical specimen