Serum procalcitonin value is useful for predicting severity of Kawasaki disease.

Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
The Pediatric Infectious Disease Journal (Impact Factor: 3.57). 12/2011; 31(5):523-5. DOI: 10.1097/INF.0b013e3182463879
Source: PubMed

ABSTRACT We measured serum procalcitonin concentrations in 160 patients suffering from Kawasaki disease. Serum procalcitonin was significantly higher in nonresponders to an initial intravenous immunoglobulin treatment than in responders. A cutoff value of procalcitonin (0.5 ng/mL) for nonresponders showed that the sensitivity was 85% and the accuracy was 64%. Multivariate logistic regression analysis revealed that procalcitonin-positive cases showed the highest risk for nonresponders.

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