Serum procalcitonin value is useful for predicting severity of Kawasaki disease.
ABSTRACT We measured serum procalcitonin concentrations in 160 patients suffering from Kawasaki disease. Serum procalcitonin was significantly higher in nonresponders to an initial intravenous immunoglobulin treatment than in responders. A cutoff value of procalcitonin (0.5 ng/mL) for nonresponders showed that the sensitivity was 85% and the accuracy was 64%. Multivariate logistic regression analysis revealed that procalcitonin-positive cases showed the highest risk for nonresponders.
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ABSTRACT: We studied the clinical, biologic (white blood cells, C-reactive protein and procalcitonin) and echocardiographic findings in 18 children hospitalized for Kawasaki disease from January 1999 until February 2006 to determine if procalcitonin is a useful marker to predict coronary aneurysms. In our study, contrary to earlier reports, elevated procalcitonin was not correlated with development of coronary aneurysms.The Pediatric Infectious Disease Journal 03/2007; 26(2):179-80. · 3.57 Impact Factor