Article

Novel poly(ADP-ribose) polymerase-1 inhibitors.

Cephalon, Inc., 145 Brandywine Parkway, West Chester, PA 19380 4245, USA.
Bioorganic & medicinal chemistry letters (impact factor: 2.65). 11/2011; 22(1):222-4. DOI:10.1016/j.bmcl.2011.11.032 pp.222-4
Source: PubMed

ABSTRACT Synthesis and activity of a series of 3-aroyl-derived analogs of novel pyrrolocarbazole 1 as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors are disclosed.

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Keywords

3-aroyl-derived analogs
 
novel pyrrolocarbazole 1
 
PARP-1