Novel poly(ADP-ribose) polymerase-1 inhibitors.
Cephalon, Inc., 145 Brandywine Parkway, West Chester, PA 19380 4245, USA.Bioorganic & medicinal chemistry letters (impact factor: 2.65). 11/2011; 22(1):222-4. DOI:10.1016/j.bmcl.2011.11.032 pp.222-4
ABSTRACT Synthesis and activity of a series of 3-aroyl-derived analogs of novel pyrrolocarbazole 1 as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors are disclosed.
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