Article

Assessment of perfluorinated compounds (PFCs) in plasma of bottlenose dolphins from two southeast US estuarine areas: Relationship with age, sex and geographic locations

National Oceanic and Atmospheric Administration, National Ocean Service, Center for Coastal Environmental Health & Biomolecular Research, 219 Fort Johnson Road, Charleston, SC 29412-9110, USA.
Marine Pollution Bulletin (Impact Factor: 2.79). 11/2011; 64(1):66-74. DOI: 10.1016/j.marpolbul.2011.10.022
Source: PubMed

ABSTRACT Plasma PFCs were measured in 157 bottlenose dolphins (Tursiops truncatus) sampled from two US southeast Atlantic sites (Charleston (CHS), SC and Indian River Lagoon (IRL), FL) during 2003-2005. ∑PFCs, perfluoroalkyl carboxylates (∑PFCAs), perfluoroalkyl sulfonates (∑PFSAs) and individual compounds were significantly higher in CHS dolphins for all age/sex categories compared to IRL dolphins. Highest ∑PFCs concentrations occurred in CHS juvenile dolphins (2340 ng/g w.w.); significantly higher than found in adults (1570 ng/g w.w. males; 1330 ng/g w.w. females). ∑PFCAs were much greater in CHS dolphins (≈ 21%) compared to IRL dolphins (≈ 7%); ∑PFSAs were 79% in CHS dolphins versus 93% in IRL dolphins. PFOS, the dominant compound, averaged 72% and 84%, respectively, in CHS and IRL dolphins. Decreasing PFC levels occurred with age on the bioaccumulation of PFCs in both sites. These observations suggest PFC accumulation in these two dolphin populations are influenced by site-specific exposures with significantly higher levels in CHS dolphins.

0 Followers
 · 
210 Views
  • Source
    • "PFAS are ubiquitous in river water, oceans, sediment, soil, and tissues of wildlife and humans (Ahrens et al., 2010a; Higgins et al., 2005;Wang et al., 2013; Giesy and Kannan, 2001; Bao et al., 2010a; Kannan et al., 2001, 2002a,b). They are potentially harmful to fresh water and marine mammals (Ishibashi et al., 2008) and have potential adverse effects in wildlife species (Hoff et al., 2005; Fair et al., 2012; Beach et al., 2005; Newsted et al., 2005, 2008; Giesy et al., 2009). Sediment is an important sink and reservoir of persistent organic pollutants and has a large impact on their distribution, transportation, and fate in the aquatic environment (Ahrens et al., 2009; Yang et al., 2011). "
    [Show abstract] [Hide abstract]
    ABSTRACT: This study investigated the concentrations and distribution of Perfluoroalkyl and polyfluoroalkyl substances (PFAS) in sediments of 12 rivers from South Bohai coastal watersheds. The highest concentrations of ΣPFAS (31.920ngg(-)(1)dw) and PFOA (29.021ngg(-)(1)dw) were found in sediments from the Xiaoqing River, which was indicative of local point sources in this region. As for other rivers, concentrations of ΣPFAS ranged from 0.218 to 1.583ngg(-)(1)dw were found in the coastal sediments and from 0.167 to 1.953ngg(-)(1)dw in the riverine sediments. Predominant PFAS from coastal and riverine areas were PFOA and PFBS, with percentages of 30% and 35%, respectively. Partitioning analysis showed the concentrations of PFNA, PFDA and PFHxS were significantly correlated with organic carbon. The results of a preliminary environmental hazard assessment showed that PFOS posed the highest hazard in the Mi River, while PFOA posed a relative higher hazard in the Xiaoqing River.
    Marine Pollution Bulletin 01/2014; 85(2). DOI:10.1016/j.marpolbul.2013.12.042 · 2.79 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Bottlenose dolphins can have iron overload (that is, hemochromatosis), and managed populations of dolphins may be more susceptible to this disease than are wild dolphins. Serum iron, total iron-binding capacity (TIBC), transferrin saturation, and ferritin were measured in 181 samples from 141 dolphins in 2 managed collections and 2 free-ranging populations. Although no iron indices increased with age among free-ranging dolphins, ferritin increased with age in managed collections. Dolphins from managed collections had higher iron, ferritin, and transferrin saturation values than did free-ranging dolphins. Dolphins with high serum iron (exceeding 300 μg/dL) were more likely to have elevated ferritin but not ceruloplasmin or haptoglobin, demonstrating that high serum levels of iron are due to a true increase in total body iron. A time-series study of 4 dolphins with hemochromatosis that were treated with phlebotomy demonstrated significant decreases in serum ferritin, iron, and TIBC between pre- and posttreatment samples; transferrin saturation initially fell but returned to prephlebotomy levels by 6 mo after treatment. Compared with those in managed collections, wild dolphins were 15 times more likely to have low serum iron (100 μg/dL or less), and this measure was associated with lower haptoglobin. In conclusion, bottlenose dolphins in managed collections are more likely to have greater iron stores than are free-ranging dolphins. Determining why this situation occurs among some dolphin populations and not others may improve the treatment of hemochromatosis in dolphins and provide clues to causes of nonhereditary hemochromatosis in humans.
    Comparative medicine 01/2012; 62(6):508-15. · 0.76 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Concentrations of Dechlorane (Dec) 603 (0.75 ng/g lipid weight (lw); mean) and Dec 602 (0.38 ng/g lw; mean) were quantified in more than 95% of the franciscana (Pontoporia blainvillei) dolphin samples, whereas the frequency of detection decreased to 75% for Dechlorane Plus (DP) (1.53 ng/g lw, mean). The presence of Chlordene Plus (CP) was also observed (0.13 ng/g lw, mean) in half of the samples. On the contrary, Dec 604, decachloropentacyclooctadecadiene (aCl(10)DP), and undecachloropentacyclooctadecadiene (aCl(11)DP) concentrations were below the limit of quantifications in all cases. To the best of our knowledge, this is the first article reporting the presence of Dec 603, Dec 602, and CP in mammals. For comparative purposes, levels of Mirex, polybrominated diphenyl ethers (PBDEs), and decabromodiphenylethane (DBDPE) are also reported. Considering geographic distribution evaluation together with the strong positive correlations found between DP and PBDEs (r(s) = 0.63; p < 0.01), highly anthropogenic areas were identified as potential sources of these chemicals in this dolphin species. However, local sources for Dec 602, 603, Mirex, CP, and DBDPE were not found indicating that in this case historical use and/or atmospheric transport and deposition may play an important role in their fate.
    Environmental Science & Technology 09/2012; 46(22). DOI:10.1021/es302934p · 5.48 Impact Factor
Show more