Cellular Mechanotransduction: Filamin A Strains to Regulate Motility

Department of Biological Sciences, Columbia University, New York, NY, USA.
Current biology: CB (Impact Factor: 9.57). 11/2011; 21(22):R916-8. DOI: 10.1016/j.cub.2011.10.020
Source: PubMed


A new study suggests that mechanical strain through the actin-binding protein filamin A leads to increased linkage between the extracellular matrix and cytoskeleton and decreased actin dynamics.

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