Article

Treatment of equine sarcoid in seven Cape mountain zebra (Equus zebra zebra).

Department of Companion Animal Clinical Studies, Private Bag X04, Faculty of Veterinary Science, Onderstepoort, University of Pretoria, South Africa.
Journal of wildlife diseases (impact factor: 1.08). 10/2011; 47(4):917-24. pp.917-24
Source: PubMed

ABSTRACT Equine sarcoid has been diagnosed in endangered Cape mountain zebra (Equus zebra zebra) in at least two game reserves in South Africa, with prevalence as high as 53% in Bontebok National Park. Seven Cape mountain zebras with sarcoids were treated with either surgical excision, 5-fluorouracil, allogenous vaccine, or a combination of 5-fluorouracil and allogenous vaccine. One of the two sarcoids on one of the 5-fluorouracil-treated zebras was left untreated. The microscopic features of the tumors evaluated showed either all or most of the typical epidermal and dermal histologic features of equine sarcoid. The zebras were examined 2 yr posttreatment to determine outcome. All sarcoids had resolved except on the zebra on which one of the sarcoids was left untreated. The efficacy of the three treatment methods in Cape mountain zebra is encouraging.

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Keywords

5-fluorouracil-treated zebras
 
allogenous vaccine
 
Bontebok National Park
 
Cape mountain zebra
 
Cape mountain zebras
 
dermal histologic features
 
endangered Cape mountain zebra
 
Equine sarcoid
 
prevalence
 
sarcoids
 
South Africa
 
surgical excision
 
three treatment methods
 
two game reserves
 
two sarcoids
 
typical epidermal
 
untreated
 
zebras
 

Hendrik J Marais