Obesity, Psychiatric Status, and Psychiatric Medications

Children's Hospital of Philadelphia, and Center for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, 3535 Market Street, Suite 3029, Philadelphia, PA 19104, USA.
The Psychiatric clinics of North America (Impact Factor: 1.87). 12/2011; 34(4):747-64. DOI: 10.1016/j.psc.2011.08.007
Source: PubMed


This article has shown that obesity is related to several psychiatric disorders, the most thoroughly researched of which is depression. In both community and clinical populations, the observed relationship is more consistent in women than in men, and is stronger in more severely obese individuals. The presence of BED also is associated with elevated risk of additional psychopathology. Longitudinal research provides evidence to support a pathway from obesity to depression, as well as one from depression to obesity. Weight loss, particularly with nonpharmacologic methods, appears to have favorable group-level effects on mood, but may be associated with adverse outcomes for some individuals. Persons who require antipsychotic medications are at risk for weight gain and metabolic abnormalities, and their management should be informed by consensus guidelines.

1 Follower
30 Reads
  • Source
    • "Thus some kinds of obesity may be considered an expression of food " addiction, " problem that typically requires a long-term treatment (Wang et al., 2001, 2002, 2004, 2009; Gearhardt et al., 2009, 2011a,b,c,d, 2012, 2013; Gearhardt and Corbin, 2011; Gearhardt and Brownell, 2013). Moreover binge eating disorder (BED) is typically connected with obesity (American Psychiatric Association, 2000; Hill, 2005; Berkowitz and Fabricatore, 2011; Gearhardt et al., 2011c; Wilson, 2011; Schag et al., 2013; Faulconbridge and Bechtel, 2014), even if not occurring exclusively in conjunction with overweight conditions . According to Hill (2005, p. 27), " it is apparent that BED is more common in the obese than in normal-weight individuals. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Obesity is currently an important public health problem of epidemic proportions (globesity). Inpatient rehabilitation interventions that aim at improving weight-loss, reducing obesity-related complications and changing dysfunctional behaviors, should ideally be carried out in a multidisciplinary context with a clinical team composed of psychologists, dieticians, psychiatrists, endocrinologists, nutritionists, physiotherapists, etc. Long-term outpatient multidisciplinary treatments are likely to constitute an essential aspect of rehabilitation. Internet-based technologies can improve long-term obesity rehabilitation within a collaborative approach by enhancing the steps specified by psychological and medical treatment protocols. These outcomes may be augmented further by the mHealth approach, through creating new treatment delivery methods to increase compliance and engagement. mHealth (m-health, mobile health) can be defined as the practice of medicine and public health, supported by mobile communication devices for health services and information. mHealth applications which can be implemented in weight loss protocols and obesity rehabilitation are discussed, taking into account future research directions in this promising area.
    Frontiers in Psychology 06/2014; 5:559. DOI:10.3389/fpsyg.2014.00559 · 2.80 Impact Factor
  • Source
    • "Weight gain is a common problem among affective disorder patients.1-6) This propensity may partly be attributable to the disease itself,6) and also to the various psychotropic medications used in its treatment, several of which have been associated with weight gain.4,6-8) "
    [Show abstract] [Hide abstract]
    ABSTRACT: A safe and effective way to control weight in patients with affective disorders is needed, and phentermine is a possible candidate. We performed a PubMed search of articles pertaining to phentermine, sibutramine, and affective disorders. We compared the studies of phentermine with those of sibutramine. The search yielded a small number of reports. Reports concerning phentermine and affective disorders reported that i) its potency in the central nervous system may be comparatively low, and ii) it may induce depression in some patients. We were unable to find more studies on the subject; thus, it is unclear presently whether phentermine use is safe in affective disorder patients. Reports regarding the association of sibutramine and affective disorders were slightly more abundant. A recent study that suggested that sibutramine may have deleterious effects in patients with a psychiatric history may provide a clue for future phentermine research. Three explanations are possible concerning the association between phentermine and affective disorders: i) phentermine, like sibutramine, may have a depression-inducing effect that affects a specific subgroup of patients, ii) phentermine may have a dose-dependent depression-inducing effect, or iii) phentermine may simply not be associated with depression. Large-scale studies with affective disorder patients focusing on these questions are needed to clarify this matter before investigation of its efficacy may be carried out and it can be used in patients with affective disorders.
    Clinical Psychopharmacology and Neuroscience 04/2013; 11(1):7-12. DOI:10.9758/cpn.2013.11.1.7
  • Source
    • "The second indirect path involves poor mental health. Cross-sectional and longitudinal research suggests that relative to non-obese individuals, obese individuals are more likely to experience depression and poor emotional health (Berkowitz & Fabricatore, 2005; Carr & Friedman, 2005; Dong et al., 2004; Roberts et al., 2000). Research indicates that obese individuals may experience poorer mental health due to the discrimination and stigmatization they experience both outside and inside the workplace (Carr & Friedman, 2005; Puhl & Brownell, 2001). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Obesity among U.S. workers is a costly problem for employers. One productivity outcome related to obesity is increased absenteeism. This national survey of employed adults (N = 2,722) explored whether poor physical health and poor mental health would explain (i.e., mediate) the relationship between obesity and absenteeism. The data revealed that 19.3% of employed U.S. adults (23.6 million workers) were obese. Being obese was positively related to increased absenteeism, as well as associated with both poor physical and poor mental health. When examined separately, both poor physical health and poor mental health were positively related to increased absenteeism. However, when examined simultaneously, poor physical health, but not poor mental health, was positively related to increased absenteeism. Finally, the relation of obesity to absenteeism was fully mediated by poor physical health. Implications for employers are discussed.
    Journal of Workplace Behavioral Health 01/2007; 22(4-4):65-79. DOI:10.1080/15555240802157403
Show more