Increased Y-chromosome resolution of haplogroup O suggests genetic ties between the Ami aborigines of Taiwan and the Polynesian Islands of Samoa and Tonga

College of Medicine, Florida International University, Miami, FL 33199, USA.
Gene (Impact Factor: 2.08). 11/2011; 492(2):339-48. DOI: 10.1016/j.gene.2011.10.042
Source: PubMed

ABSTRACT The Austronesian expansion has left its fingerprint throughout two thirds of the circumference of the globe reaching the island of Madagascar in East Africa to the west and Easter Island, off the coast of Chile, to the east. To date, several theories exist to explain the current genetic distribution of Austronesian populations, with the "slow boat" model being the most widely accepted, though other conjectures (i.e., the "express train" and "entangled bank" hypotheses) have also been widely discussed. In the current study, 158 Y chromosomes from the Polynesian archipelagos of Samoa and Tonga were typed using high resolution binary markers and compared to populations across Mainland East Asia, Taiwan, Island Southeast Asia, Melanesia and Polynesia in order to establish their patrilineal genetic relationships. Y-STR haplotypes on the C2 (M38), C2a (M208), O1a (M119), O3 (M122) and O3a2 (P201) backgrounds were utilized in an attempt to identify the differing sources of the current Y-chromosomal haplogroups present throughout Polynesia (of Melanesian and/or Asian descent). We find that, while haplogroups C2a, S and K3-P79 suggest a Melanesian component in 23%-42% of the Samoan and Tongan Y chromosomes, the majority of the paternal Polynesian gene pool exhibits ties to East Asia. In particular, the prominence of sub-haplogroup O3a2c* (P164), which has previously been observed at only minimal levels in Mainland East Asians (2.0-4.5%), in both Polynesians (ranging from 19% in Manua to 54% in Tonga) and Ami aborigines from Taiwan (37%) provides, for the first time, evidence for a genetic connection between the Polynesian populations and the Ami.

1 Follower
  • Source
    • "Recently, a study of Y chromosome variation in Tongans and Samoans has identified a high frequency of the Asian derived O3a2c-P164 Y chromosome haplotype, reaching levels as high as 53% in Tonga. This haplotype was also found in the Ami indigenous peoples of Taiwan, providing the first direct link between Taiwan and Polynesia (Mirabal et al., 2012). Unfortunately, to date, few other populations in Island Southeast Asia and the Pacific have been assayed for the P164 marker, and it is possible that many more of the Pacific Y chromosomes that are on the O3 branch may also carry this marker. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The Pacific region provides unique opportunities to study human evolution including through analyses of ancient DNA. While some of the earliest studies involving ancient DNA from skeletal remains focused on Pacific samples, in the following 25 years, several factors meant that little aDNA research, particularly research focused on human populations, has emerged. This paper briefly presents the genetic evidence for population origins, reviews what ancient DNA work has been undertaken to address human history and evolution in the Pacific region, and argues that the future is bright but research requires a collaborative approach between academic disciplines but also with local communities.
    Journal of Human Evolution 02/2015; 79. DOI:10.1016/j.jhevol.2014.10.017 · 3.87 Impact Factor
  • Source
    • "MBE which allows for sex-biased admixture between migrants of Asian ancestry (possibly from Taiwan) with existing Melanesian populations with respect to Polynesian origins (Kayser et al. 2000, 2008; Wollstein et al. 2010; Mirabal et al. 2012). In addition, some studies offered a differing perspective: possible earlier migration(s) from the Asian mainland during the late-Pleistocene to early-Holocene period, which predates the Austronesian expansion, based on mtDNA (Hill et al. 2006, 2007) and Y-chromosomal (Karafet et al. 2010) analyses of island Southeast Asian populations. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The population history of the indigenous populations in island Southeast Asia is generally accepted to have been shaped by two major migrations: the ancient "Out of Africa" migration ∼50,000 years before present (YBP) and the relatively recent "Out of Taiwan" expansion of Austronesian agriculturalists approximately 5,000 YBP. The Negritos are believed to have originated from the ancient migration, whereas the majority of island Southeast Asians are associated with the Austronesian expansion. We determined 86 mitochondrial DNA (mtDNA) complete genome sequences in four indigenous Malaysian populations, together with a reanalysis of published autosomal single-nucleotide polymorphism (SNP) data of Southeast Asians to test the plausibility and impact of those migration models. The three Austronesian groups (Bidayuh, Selatar, and Temuan) showed high frequencies of mtDNA haplogroups, which originated from the Asian mainland ∼30,000-10,000 YBP, but low frequencies of "Out of Taiwan" markers. Principal component analysis and phylogenetic analysis using autosomal SNP data indicate a dichotomy between continental and island Austronesian groups. We argue that both the mtDNA and autosomal data suggest an "Early Train" migration originating from Indochina or South China around the late-Pleistocene to early-Holocene period, which predates, but may not necessarily exclude, the Austronesian expansion.
    Molecular Biology and Evolution 06/2012; 29(11):3513-27. DOI:10.1093/molbev/mss169 · 14.31 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Taiwanese aborigines have been deemed the ancestors of Austronesian speakers which are currently distributed throughout two-thirds of the globe. As such, understanding their genetic distribution and diversity as well as their relationship to mainland Asian groups is important to consolidating the numerous models that have been proposed to explain the dispersal of Austronesian speaking peoples into Oceania. To better understand the role played by the aboriginal Taiwanese in this diaspora, we have analyzed a total of 451 individuals belonging to nine of the tribes currently residing in Taiwan, namely the Ami, Atayal, Bunun, Paiwan, Puyuma, Rukai, Saisiyat, Tsou, and the Yami from Orchid Island off the coast of Taiwan across 15 autosomal short tandem repeat loci. In addition, we have compared the genetic profiles of these tribes to populations from mainland China as well as to collections at key points throughout the Austronesian domain. While our results suggest that Daic populations from Southern China are the likely forefathers of the Taiwanese aborigines, populations within Taiwan show a greater genetic impact on groups at the extremes of the current domain than populations from Indonesia, Mainland, or Southeast Asia lending support to the "Out of Taiwan" hypothesis. We have also observed that specific Taiwanese aboriginal groups (Paiwan, Puyuma, and Saisiyat), and not all tribal populations, have highly influenced genetic distributions of Austronesian populations in the pacific and Madagascar suggesting either an asymmetric migration out of Taiwan or the loss of certain genetic signatures in some of the Taiwanese tribes due to endogamy, isolation, and/or drift. Am J Phys Anthropol, 2012. © 2012 Wiley Periodicals, Inc.
    American Journal of Physical Anthropology 04/2013; 150(4). DOI:10.1002/ajpa.22226 · 2.51 Impact Factor
Show more