Article

Implications of the alpha dispersion for studies on interaction of tobacco smoke--corneal tissue.

Department of Bionics and Bioimpedance, Poznań University of Medical Sciences, Poznań, Poland.
Colloids and surfaces. B, Biointerfaces (impact factor: 2.6). 02/2012; 90:109-12. DOI:10.1016/j.colsurfb.2011.10.007 pp.109-12
Source: PubMed

ABSTRACT In this work, we have carried out a dielectric study to determine the effect of tobacco smoke on the rat corneal function. Measurements were performed over the frequency range of 500 Hz-100 kHz in air and at the temperature of 35°C. The frequency dependencies of the loss tangent for both healthy and smoky cornea exhibit two peaks with different width occurring as a narrow at 2 kHz and a broad at around 16 kHz. The distribution parameter α at 2 kHz has a value of about 0.3, which increases to 0.6 at 16 kHz. The magnitude of the permittivity decrement at 2 and 16 kHz is about two and four times higher, respectively, for the smoky cornea than that for the healthy one. These dielectric studies indicate that the present method is useful in detection of the effect of tobacco smoke exposure on the corneal behavior.

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Keywords

2 kHz
 
corneal behavior
 
dielectric studies
 
distribution parameter α
 
frequency dependencies
 
frequency range
 
healthy
 
loss tangent
 
narrow
 
permittivity decrement
 
present method
 
rat corneal function
 
smoky cornea
 
smoky cornea exhibit
 
times higher
 
tobacco smoke
 
tobacco smoke exposure