Article

Brain-Gut Axis: From Basic Understanding to Treatment of IBS and Related Disorders

Clinical Enteric Neuroscience Translational and Epidemiological Research, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Journal of pediatric gastroenterology and nutrition (Impact Factor: 2.87). 10/2011; 54(4):446-53. DOI: 10.1097/MPG.0b013e31823d34c3
Source: PubMed

ABSTRACT The present review describes advances in understanding the mechanisms and provide an update of present and promising therapy directed at the gut or the brain in the treatment of irritable bowel syndrome (IBS). The diagnosis of IBS typically is based on identification of symptoms, such as the Rome III criteria for IBS in adults and children. The criteria are similar in children and adults. The focus of the present review is the bowel dysfunction associated with IBS.

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