Very little high-quality evidence to support most medications for children with autism spectrum disorders
Nationwide Children's Hospital, Columbus, Ohio, USA.The Journal of pediatrics (Impact Factor: 3.74). 11/2011; 159(5):872-3. DOI: 10.1016/j.jpeds.2011.09.005
- [Show abstract] [Hide abstract]
ABSTRACT: Medication adherence in children is poor, particularly among those with chronic or mental health disorders. However, adherence has not been fully assessed in autism spectrum disorders (ASDs). The validated proportion of days covered method was used to quantify adherence to psychotropic medication in Medicaid-eligible children who met diagnostic criteria for ASD between 2000 and 2008 (N = 628). Among children prescribed attention deficit hyperactivity disorder (ADHD) medications, antidepressants, or antipsychotics, 44, 40 and 52 % were adherent respectively. Aggressive behaviors and abnormalities in eating, drinking, and/or sleeping, co-occurring ADHD, and the Medication Regimen Complexity Index were the most significant predictors of adherence rather than demographics or core deficits of ASD. Identifying barriers to adherence in ASD may ultimately lead to improved treatment outcomes.Journal of Autism and Developmental Disorders 06/2014; 44(11). DOI:10.1007/s10803-014-2156-0 · 3.34 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.