Article

[The target of Musca domestica cecropin on human hepatocellular carcinoma BEL-7402 cells].

School of Basic Courses, Guangdong Pharmaceutical University, Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 08/2011; 29(4):271-3.
Source: PubMed

ABSTRACT Human hepatocellular carcinoma BEL-7402 cells were treated with 50 micromol/L Musca domestica cecropin for 12 h, and observed under scanning electron microscope. The effect of Musca domestica cecropin labeled with FITC (FITC-cecropin) on BEL-7402 cells was detected by laser scanning confocal microscopy. The scanning electron microscopy showed that most microvilli on the surface of BEL-7402 cells disappeared at 12 h after cecropin treatment. The laser scanning confocal microscopy revealed that most FITC-cecropin combined with BEL-7402 cell membrane, and partly in the cytoplasm.

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Keywords

50 micromol/L Musca domestica cecropin
 
cytoplasm
 
Human hepatocellular carcinoma BEL-7402 cells
 
laser scanning confocal microscopy
 
Musca domestica cecropin
 
scanning electron microscope
 
scanning electron microscopy
 

Xiao-Bao Jin