Bioactive compounds extracted from Indian wild legume seeds: Antioxidant and type II diabetesrelated enzyme inhibition properties

Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany.
International Journal of Food Sciences and Nutrition (Impact Factor: 1.21). 03/2012; 63(2):242-5. DOI: 10.3109/09637486.2011.621413
Source: PubMed


Seven different wild legume seeds (Acacia leucophloea, Bauhinia variegata, Canavalia gladiata, Entada scandens, Mucuna pruriens, Sesbania bispinosa and Tamarindus indica) from various parts of India were analyzed for total free phenolics, l-Dopa (l-3,4 dihydroxyphenylalanine), phytic acid and their antioxidant capacity (ferric-reducing antioxidant power [FRAP] and 2,2-diphenyl-1-picrylhydrazyl [DPPH] assay) and type II diabetes-related enzyme inhibition activitiy (α-amylase). S. bispinosa had the highest content in both total free phenolics and l-Dopa, and relatively low phytic acid when compared with other seeds. Phytic acid content, being highest in E. scandens, M. pruriens and T. indica, was highly predictive for FRAP (r = 0.47, p < 0.05) and DPPH (r = 0.66, p < 0.001) assays. The phenolic extract from T. indica and l-Dopa extract from E. scandens showed significantly higher FRAP values among others. All seed extracts demonstrated a remarkable reducing power (7-145 mM FeSO4 per mg extract), DPPH radical scavenging activity (16-95%) and α-amylase enzyme inhibition activity (28-40%).

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    • "Sasipriya G et al. reported the effect of different processing methods on antioxidant activity in the seed kernel (Sasipriya G and Siddhuraju P, 2012). Gautam B et al. reported the bioactive compounds, antioxidant activity and type II diabetes-related enzyme inhibition properties of the seed of the plant (Gautam B et al., 2012). Vadivel et al. reported the total free phenolic content of the wild legume of the plant (Vadivel et al., 2011). "
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