Article

Camptocormia in Japanese patients with Parkinson's disease: a multicenter study.

Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
Movement Disorders (impact factor: 4.51). 09/2011; 26(14):2567-71. DOI:10.1002/mds.23955 pp.2567-71
Source: PubMed

ABSTRACT The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients.
Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size.
We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia.
Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05).
Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms.

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Keywords

22 patients
 
531 PD patients
 
autonomic symptoms
 
camptocormia
 
constipation
 
disease duration
 
disease severity
 
higher frequencies
 
higher L-dopa dose
 
higher levodopa
 
L-dopa
 
large population
 
patients
 
PD patients
 
previous epidemiological reports
 
prominent phenomenon
 
sample size
 
severe motor symptoms
 
urinary incontinence
 
± standard deviation