Comparison of the INNO-LiPA and PapType assays for detection of human papillomavirus in archival vulva dysplasia and/or neoplasia tissue biopsy specimens.

Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Victoria 3052, Australia.
Journal of clinical microbiology (Impact Factor: 4.16). 09/2011; 49(11):3980-2. DOI:10.1128/JCM.00516-11
Source: PubMed

ABSTRACT INNO-LiPA and PapType human papillomavirus (HPV) genotyping assays were compared for detection of HPV genotypes on archival vulvar tissue. The INNO-LiPA assay detected 49 HPV-16 infections, compared with 47 detected by the PapType assay. The INNO-LiPA assay detected amplifiable DNA in 59 (91%) biopsy specimens, compared with 57 (88%) specimens for which amplifiable DNA was detected by the PapType assay. The two genotyping assays were highly comparable.

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