Translational Research What Does It Mean?

Department of Paediatrics, University of Melbourne, Royal Children's Hospital and Murdoch Childrens Research Institute, Flemington Road, Parkville, Victoria, Australia. Andrew.
Anesthesiology (Impact Factor: 5.88). 09/2011; 115(5):909-11. DOI: 10.1097/ALN.0b013e3182337a5e
Source: PubMed
2 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: The future of pediatric anesthesia can be thought of in terms of what will happen to the practice of anesthesia, or what will happen to the profession of pediatric anesthesia. The profession will change both under external forces, and by how pediatric anesthetists themselves decide to shape of the profession. The largest external force is likely to be cost. The profession will increasingly be expected to maintain efficiency without compromising quality. Other future issues include credentialing, training and the role of the anesthetists beyond the operating room. It's harder to predict how the practice of pediatric anesthesia might change. New drugs may change practice, though perhaps it's more likely that practice will change with better use of existing drugs. New technologies will have an impact in monitoring and in the gathering and dissemination of information. Practice will also change with changes in surgery. Perhaps the biggest changes will come in areas with the greatest unknowns; neonatal anesthesia is an area with many unknowns and thus great potential for change and improvement.
    Pediatric Anesthesia 06/2012; 22(6):570-2. DOI:10.1111/j.1460-9592.2012.03887.x · 1.85 Impact Factor
  • Source
    09/2012; 7(2):66-7. DOI:10.5469/neuroint.2012.7.2.66
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The label 'Translational Research' (TR) has become ever more popular in the biomedical domain in recent years. It is usually presented as an attempt to bridge a supposed gap between knowledge produced at the lab bench and its use at the clinical bedside. This is claimed to help society harvest the benefits of its investments in scientific research. The rhetorical as well as moral force of the label TR obscure, however, that it is actually used in very different ways. In this paper, we analyse the scientific discourse on TR, with the aim to disentangle and critically evaluate the different meanings of the label. We start with a brief reconstruction of the history of the concept. Subsequently, we unravel how the label is actually used in a sample of scientific publications on TR and examine the presuppositions implied by different views of TR. We argue that it is useful to distinguish different views of TR on the basis of three dimensions, related to (1) the construction of the 'translational gap'; (2) the model of the translational process; and (3) the cause of the perceived translational gap. We conclude that the motive to make society benefit from its investments in biomedical science may be laudable, but that it is doubtful whether the dominant views of TR will contribute to this end.
    Health Care Analysis 12/2012; 23(1). DOI:10.1007/s10728-012-0236-x · 1.02 Impact Factor
Show more