Article

Control of coronary blood flow during exercise.

Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195-7920, USA.
Exercise and sport sciences reviews (Impact Factor: 3.23). 08/2011; 40(1):37-42. DOI: 10.1097/JES.0b013e3182348cdd
Source: PubMed

ABSTRACT During exercise, coronary blood flow increases to match the augmented myocardial oxygen demand because of tachycardia. Coronary vasodilation during exercise is via a combination of feedforward and feedback control mechanisms. Feedforward control is mediated by sympathetic β-adrenoceptor vasodilation. Feedback vasodilator control is via a novel hypothesis where adenine nucleotides released from red blood cells act on endothelial purinergic receptors.

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