A Rare Location of Metastasis from Prostate Cancer: Hydronephrosis Associated with Ureteral Metastasis

Department of Urology, St. Joseph's Mecial Center, University of Regensburg, Landshuter Straße 65, 93053 Regensburg, Germany.
Advances in Urology 01/2012; 2012(5):656023. DOI: 10.1155/2012/656023
Source: PubMed


Prostate carcinoma is a very rare origin of metastatic disease in the ureter. We report a case of a 74-year-old man who presented in November 2008 initially with flank pain and lower urinary tract symptoms. Diagnostic investigation revealed a skeletal metastasizing prostate carcinoma, and the cause for the flank pain was a hydronephrosis due to ureteral metastasis diagnosed by biopsy. Antihormonal treatment led to disappearance of the hydronephrosis; however, further progress finally ended in acute liver failure with patient's death in July 2010.

Download full-text


Available from: Stefan Denzinger, Oct 10, 2015
37 Reads
  • Source
    • ". Since then, seven new cases were reported in the recent ten years [3] [4] [5] [6] [7] [8] [9] (Table 1). Among these cases, chief complaints resulting from ureteral obstruction, such as flank pain and enuresis, account for the main part. "
    [Show abstract] [Hide abstract]
    ABSTRACT: This is a case report of a 67-year-old patient with distant metastasis of prostate cancer to the right ureter which caused hydronephrosis. At the beginning, both of the cytology of the morning urine and imaging findings were consistent with urothelial carcinoma. Nephroureterectomy was subsequently performed. Interestingly, the pathological examination of the excised ureter revealed that the malignancy was derived from the prostate. No skeletal metastasis was detected. However, after four months of follow-up, several abnormal signal shadows were reported in skeletal scintigraphy and the prostate specific antigen (PSA) was gradually increasing. We present such a case for its unique presentation. A review of the literature is also provided.
    08/2014; 2014:230852. DOI:10.1155/2014/230852
  • [Show abstract] [Hide abstract]
    ABSTRACT: Les métastases urétérales secondaires à un adénocarcinome prostatique sont très rares. Nous rapportons un cas de métastase urétérale droite d’un cancer de prostate découverte chez un homme de 66 ans. Seulement dix cas de métastases urétérales de cancer de prostate ont été rapportés ces 30 dernières années dans la littérature. Les patients avaient le plus souvent un cancer de prostate multimétastatique. Le traitement local n’est pas standardisé. Il semble pertinent de proposer une hormonothérapie seule en première intention.
    Progrès en Urologie 12/2013; 23(16):1443–1448. DOI:10.1016/j.purol.2013.05.003 · 0.66 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Prostate cancer is one of the most common male malignancies, but it rarely metastasizes to the proximal ureter. We report a case of a 76-year-old man who presented with flank pain and lower urinary tract symptoms. Abdominal computed tomography scan revealed multiple filling defects at the middle of the left ureter, enlarged retroperitoneal lymph nodes, and probable psoas invasion. The patient underwent nephroureterectomy with excision of a cuff of bladder, and was found to have an adhesion between the middle part of left ureter and psoas intraoperatively. The pathological examination displayed positive immunohistochemical staining with prostate-specific antigen and prostate acid phostate, supporting the diagnosis of metastatic ureteral tumour from prostate cancer. In this case, periureteral soft tissue and ureteral muscular layer were infiltrated by metastatic tumour, whereas the mucosa was spared. The periureteral lymphatic pathway played an important role in the metastatic procedure of prostate cancer to the proximal ureter.
    11/2014; 8(11-12):E859-E861. DOI:10.5489/cuaj.2169
Show more