Article

Immunosuppressive therapy in children.

Department of Paediatrics, Institute of Medical Sciences, BHU, Varanasi 221005.
Journal of the Indian Medical Association 02/2011; 109(2):101-2, 104-7. pp.101-2, 104-7
Source: PubMed

ABSTRACT The treatment of auto-immune diseases is evolving and newer agents become available. This review will outline treatment options in children with auto-immune disorders. Treatment with current corticosteroids and azathioprine works in majority but issues of intolerance and incomplete response arise, which led to window of newer immunosuppressants including mycophenolate mofetil, cyclosporine, tacrolimus, sirolimus, and various antibodies of human and animal origin. The newer agents have been studied in fewer numbers of children, so they are not first-line treatment yet but do have a clear role in patients with intolerance or incomplete response to standard therapy.

0 0
 · 
0 Bookmarks
 · 
34 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

animal origin
 
auto-immune diseases
 
auto-immune disorders
 
children
 
current corticosteroids
 
cyclosporine
 
incomplete response
 
mycophenolate mofetil
 
newer immunosuppressants
 
patients
 
tacrolimus
 
various antibodies