Coumarin-Cu(II) ensemble-based cyanide sensing chemodosimeter.
ABSTRACT An "ensemble"-based chemodosimeter 1-Cu(II) for cyanide detection is reported. 1-Cu(II) can recognize a cyanide ion over other anionic species to show a marked fluorescence enhancement under aqueous conditions. "Off-on" fluorescence change of 1-Cu(II) is proceeded by addition of cyanide, which induces decomplexation of the Cu(II) ion from nonfluorescent 1 followed by hydrolytic cleavage of the resulted Schiff base to give a strongly fluorescent coumarinaldehyde (2). The selective detection of cyanide with 1-Cu(II) for biological application was also performed in HepG2 cells.
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ABSTRACT: A new Ru(II) complex is described which serves as a luminescence lifetime-based sensor for fluoride and cyanide anions (KF = 640 000 mol-1, KCN = 430 000 mol-1). This chromophore displays observable changes in its UV-vis and steady-state luminescence spectra upon cyanide binding. Prior to cyanide addition, this complex exhibits a single-exponential lifetime (tau = 377 +/- 20 ns). With increasing cyanide concentrations, the intensity decays are composed of two exponentials: long tau (320-370 ns) and short tau (13-17 ns). The average lifetimes shorten as a function of cyanide concentration since the fractional intensity shifts from an initial dominant long lifetime component to the short lifetime component. This work represents the first example of a direct method for the luminescence lifetime-based sensing of anions.Journal of the American Chemical Society 07/2002; 124(22):6232-3. · 10.68 Impact Factor
- Chemical Reviews 09/1997; 97(5):1515-1566. · 41.30 Impact Factor
- Chemical Reviews 12/2003; 103(11):4419-76. · 41.30 Impact Factor