[Combined pharmacological-surgical treatment in exudative age-related macular degeneration].

Małgorzata Figurska, Jacek Robaszkiewicz, Agnieszka Bogdan-Bandurska

Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie.

Journal Article: Klinika oczna 01/2011; 113(1-3):56-9.

Abstract

The aim of this paper is to present the early phase of treating exudative age-releted macular degeneration (AMD)--coexisting witch vitreoretinal pathology--with combined pharmacological-surgical therapy.
Our observation is based on one clinical case of combined therapy: pars planavitrectomy (PPV) and one intravitrealranibizumab injection. Observation is being carried on larger patient group according to the treatment scheme presented In this paper. RESUTS: In this case described combined pharmacological-surgical therapy allowed a significant improvement in visual acuity and closure of choroidal neovascularization (CNV), leakage confirmed by fluorescein angiography (FA) and optical coherence tomography (AMD). The treatment is being continued--another ranibizumab injection according to PRONTO study reinjection criteria.
The pathomechanism of exudative AMD and coexistance of vitreoretinal pathology implications confirm reasonability of combined therapy.Due to actual clinical studies: the pharmacological -surgical treatment reduces the number of required intravitreal anti-VEGF agents injections. To confirm this observation we need to perform large randomised clinical studies.

Source: PubMed

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Keywords

actual clinical studies
 
AMD
 
choroidal neovascularization
 
clinical case
 
CNV
 
exudative AMD
 
fluorescein angiography
 
intravitreal anti-VEGF agents injections
 
intravitrealranibizumab injection
 
large randomised clinical studies
 
larger patient group
 
leakage
 
optical coherence tomography
 
pharmacological -surgical treatment
 
pharmacological-surgical therapy
 
PRONTO study reinjection criteria
 
therapy.Due
 
treatment scheme
 
visual acuity
 
vitreoretinal pathology implications